Literature DB >> 1795936

Compatibility of bupivacaine and iohexol in two mixtures for paediatric regional anaesthesia.

P Van Asten1, J H Glerum, E R Spaanderman, J Van Niekerk, A Van Dijk.   

Abstract

The compatibility of bupivacaine (0.25% and 0.125% wt/vol) with iohexol 300 mg I/ml was investigated. At room temperature bupivacaine does not decompose in these mixtures over a period of 24 h. pH Values (7.10 and 7.33), clarity, osmolality (370 and 379 mOsm/kg) and buffer capacity (0.035 ml and 0.010 ml 0.1000 mol/l NaOH per 10 ml) meet requirements for epidural injection. Both mixtures are suitable for epidurography.

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Year:  1991        PMID: 1795936     DOI: 10.1007/BF02015580

Source DB:  PubMed          Journal:  Pharm Weekbl Sci        ISSN: 0167-6555


  3 in total

Review 1.  Local anaesthetic techniques in paediatric surgery.

Authors:  D S Arthur; L R McNicol
Journal:  Br J Anaesth       Date:  1986-07       Impact factor: 9.166

2.  Spinal anesthesia in premature infants recovering from respiratory distress syndrome.

Authors:  E V Harnik; G R Hoy; S Potolicchio; D R Stewart; R E Siegelman
Journal:  Anesthesiology       Date:  1986-01       Impact factor: 7.892

3.  Spinal anesthesia for surgery in the high-risk infant.

Authors:  J C Abajian; R W Mellish; A F Browne; F M Perkins; D H Lambert; J E Mazuzan
Journal:  Anesth Analg       Date:  1984-03       Impact factor: 5.108

  3 in total

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