Literature DB >> 17959342

Glutathione levels and immune responses in tuberculosis patients.

Vishwanath Venketaraman1, Ariel Millman, Marwa Salman, Shobha Swaminathan, Mary Goetz, Alfred Lardizabal, Nancy D Connell.   

Abstract

Glutathione levels are significantly reduced in peripheral blood mononuclear cells and red blood cells isolated from tuberculosis patients. Treatment of blood cultures from tuberculosis patients with N-acetyl cysteine, a glutathione precursor, was associated with improved control of intracellular M. tuberculosis infection. N-acetyl-cysteine treatment decreased the levels of IL-10, IL-6, TNF-alpha and IL-1, in blood cultures derived from tuberculosis patients, favoring the host immune cells to successfully control M. tuberculosis replication.

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Year:  2007        PMID： 17959342     DOI： 10.1016/j.micpath.2007.09.002

Source DB:  PubMed          Journal:  Microb Pathog        ISSN： 0882-4010            Impact factor:   3.738


  37 in total

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Authors:  Haoyu Sun; Cheng Sun; Zhigang Tian; Weihua Xiao
Journal:  Cell Mol Immunol       Date:  2013-04-08       Impact factor: 11.530

2.  Control of Mycobacterium tuberculosis growth by activated natural killer cells.

Authors:  C Guerra; K Johal; D Morris; S Moreno; O Alvarado; D Gray; M Tanzil; D Pearce; V Venketaraman
Journal:  Clin Exp Immunol       Date:  2012-04       Impact factor: 4.330

3.  An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages.

Authors:  Arunava Dasgupta; Kamakshi Sureka; Devrani Mitra; Baisakhee Saha; Sourav Sanyal; Amit K Das; Parul Chakrabarti; Mary Jackson; Brigitte Gicquel; Manikuntala Kundu; Joyoti Basu
Journal:  PLoS One       Date:  2010-08-17       Impact factor: 3.240

4.  Glutathione Depletion Is Linked with Th2 Polarization in Mice with a Retrovirus-Induced Immunodeficiency Syndrome, Murine AIDS: Role of Proglutathione Molecules as Immunotherapeutics.

Authors:  Serena Brundu; Linda Palma; Giusi Giada Picceri; Daniela Ligi; Chiara Orlandi; Luca Galluzzi; Laura Chiarantini; Anna Casabianca; Giuditta Fiorella Schiavano; Martina Santi; Ferdinando Mannello; Kathy Green; Michaël Smietana; Mauro Magnani; Alessandra Fraternale
Journal:  J Virol       Date:  2016-07-27       Impact factor: 5.103

5.  Ferroptosis in infection, inflammation, and immunity.

Authors:  Xin Chen; Rui Kang; Guido Kroemer; Daolin Tang
Journal:  J Exp Med       Date:  2021-05-12       Impact factor: 14.307

6.  Role of glutathione in immunity and inflammation in the lung.

Authors:  Pietro Ghezzi
Journal:  Int J Gen Med       Date:  2011-01-25

7.  Atherosclerosis: pathogenesis and increased occurrence in individuals with HIV and Mycobacterium tuberculosis infection.

Authors:  Timothy Guilford; Devin Morris; Dennis Gray; Vishwanath Venketaraman
Journal:  HIV AIDS (Auckl)       Date:  2010-10-29

8.  Effects of Oral Liposomal Glutathione in Altering the Immune Responses Against Mycobacterium tuberculosis and the Mycobacterium bovis BCG Strain in Individuals With Type 2 Diabetes.

Authors:  Kimberly To; Ruoqiong Cao; Aram Yegiazaryan; James Owens; Timothy Nguyen; Kayvan Sasaninia; Charles Vaughn; Mohkam Singh; Edward Truong; Albert Medina; Edith Avitia; Jose Villegas; Christal Pham; Airani Sathananthan; Vishwanath Venketaraman
Journal:  Front Cell Infect Microbiol       Date:  2021-06-03       Impact factor: 5.293

9.  Extracellular glutathione decreases the ability of Burkholderia cenocepacia to penetrate into epithelial cells and to induce an inflammatory response.

Authors:  Melania D'Orazio; Francesca Pacello; Andrea Battistoni
Journal:  PLoS One       Date:  2012-10-19       Impact factor: 3.240

Review 10.  Understanding the Reciprocal Interplay Between Antibiotics and Host Immune System: How Can We Improve the Anti-Mycobacterial Activity of Current Drugs to Better Control Tuberculosis?

Authors:  Hyun-Eui Park; Wonsik Lee; Min-Kyoung Shin; Sung Jae Shin
Journal:  Front Immunol       Date:  2021-06-28       Impact factor: 7.561
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