| Literature DB >> 17959274 |
Ivan R Green1, Felismino E Tocoli, Sang Hwa Lee, Ken-ichi Nihei, Isao Kubo.
Abstract
On the basis of antibacterial anacardic acids, 6-pentadecenylsalicylic acids, isolated from the cashew apple, Anacardium occidentale L. (Anacardiaceae), a series of 6-alk(en)ylsalicylic acids were synthesized and tested for their antibacterial activity against Streptococcus mutans ATCC 25175. Among them, 6-(4',8'-dimethylnonyl)salicylic acid was found to exhibit the most potent antibacterial activity against this cariogenic bacterium with the minimum inhibition concentration (MIC) of 0.78 microg/ml.Entities:
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Year: 2007 PMID： 17959274 DOI： 10.1016/j.ejmech.2007.08.012
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514