Insect tachykinin-like peptide: distribution of leucokinin immunoreactive neurons in the cockroach and blowfly brains.

Antisera were raised against leucokinin I, a cockroach myotropic neuropeptide with some resemblance to vertebrate tachykinins. These antisera were used for immunocytochemical mapping of neurons and neurosecretory cells in the brains of a cockroach and a blowfly species. The leucokinin immunoreactive cells are distinct from neurons that can be labeled with antisera against vertebrate type tachykinins. It is suggested that leucokinin-like peptides may have roles as neurohormones and neuromodulators in the insect nervous system.