| Literature DB >> 179579 |
S B Rodan, G A Rodan, R I Sha'afi.
Abstract
The presence of adenylate cyclase (ATP pyrophosphate-lyase (cyclizing) EC 4.6.1.1) activity was demonstrated in human erythrocyte ghosts and was found to be around 3 pmol adenosine 3',5'-monophosphate (cyclic AMP) - 2 h-1 - mg-1 protein. This enzymatic activity is strongly stimulated by NaF and 5'-guanylimidodiphosphate, is slightly stimulated by epinephrine, norepinephrine, isoproterenol, and prostaglandin E1 and is inhibited by calcium. The hormone stimulation is not potentiated by 5'-guanylylimidodiphosphate.Entities:
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Year: 1976 PMID： 179579 DOI： 10.1016/0304-4165(76)90059-3
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002