Literature DB >> 17957298

pH-Controllable drug release using hydrogel encapsulated mesoporous silica.

S-W Song1, K Hidajat, S Kawi.   

Abstract

Amine-functionalized mesoporous SBA-15 silica loaded with bovine serum albumin (BSA) has been successfully encapsulated with a thin layer coating of poly(acrylic acid) PAA, with the entrapped BSA being released from the PAA-encapsulated SBA-15 at the higher pH value of 7.4 rather than at the lower pH value of 1.2. This novel drug delivery system has a potential application in the release of protein drug to the site of higher pH value, such as small intestine or colon.

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Year:  2007        PMID： 17957298     DOI： 10.1039/b707626f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  The biocompatibility of mesoporous silicates.

Authors:  Sarah P Hudson; Robert F Padera; Robert Langer; Daniel S Kohane
Journal:  Biomaterials       Date:  2008-10       Impact factor: 12.479

Review 2.  Translational Applications of Hydrogels.

Authors:  Santiago Correa; Abigail K Grosskopf; Hector Lopez Hernandez; Doreen Chan; Anthony C Yu; Lyndsay M Stapleton; Eric A Appel
Journal:  Chem Rev       Date:  2021-05-03       Impact factor: 60.622

3.  Bioresponsive mesoporous silica nanoparticles for triggered drug release.

Authors:  Neetu Singh; Amrita Karambelkar; Luo Gu; Kevin Lin; Jordan S Miller; Christopher S Chen; Michael J Sailor; Sangeeta N Bhatia
Journal:  J Am Chem Soc       Date:  2011-11-18       Impact factor: 15.419

4.  Enhanced antifungal efficacy of tebuconazole using gated pH-driven mesoporous nanoparticles.

Authors:  Núria Mas; Irene Galiana; Silvia Hurtado; Laura Mondragón; Andrea Bernardos; Félix Sancenón; María D Marcos; Pedro Amorós; Nuria Abril-Utrillas; Ramón Martínez-Máñez; José Ramón Murguía
Journal:  Int J Nanomedicine       Date:  2014-05-23

5.  Construction of pH-responsive and up-conversion luminescent NaYF₄:Yb³⁺/Er³⁺@SiO₂@PMAA nanocomposite for colon targeted drug delivery.

Authors:  Boshi Tian; Shaohua Liu; Wei Lu; Lin Jin; Qingfeng Li; Yurong Shi; Chunyang Li; Zhenling Wang; Yaping Du
Journal:  Sci Rep       Date:  2016-02-19       Impact factor: 4.379

6.  Synthesis of Calcium Bisphosphonate/Calcium Polyacrylate Spheres for Gene Delivery.

Authors:  Xiaona Wei; Xiaodan Liu; Xue Wang; Yuanyuan Bao; Xin Shi; Liwei Sun
Journal:  ACS Omega       Date:  2017-05-11

7.  Preparation of RGD Peptide/Folate Acid Double-Targeted Mesoporous Silica Nanoparticles and Its Application in Human Breast Cancer MCF-7 Cells.

Authors:  Huijie Yan; Yun You; Xinjian Li; Lei Liu; Fengqian Guo; Qiongling Zhang; Dewen Liu; Yan Tong; Shilan Ding; Jinyu Wang
Journal:  Front Pharmacol       Date:  2020-06-16       Impact factor: 5.810

8.  Construction of versatile multilayered composite nanoparticles from a customized nanogel template.

Authors:  Jian Zhang; Jinpeng Jia; Jimin P Kim; Fei Yang; Xing Wang; Hong Shen; Sijia Xu; Jian Yang; Decheng Wu
Journal:  Bioact Mater       Date:  2017-07-01
  8 in total

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