| Literature DB >> 17956720 |
André Nussenzweig1, Michel C Nussenzweig.
Abstract
Chromosomal translocations between antigen receptor loci and oncogenes are a hallmark of lymphoid cancers. Several new studies now reveal that programmed DNA breaks created during assembly of antigen receptor genes can be channeled into an alternative DNA end-joining pathway that is implicated in the chromosomal translocations of lymphoid cancers (Corneo et al., 2007; Soulas-Sprauel et al., 2007; Yan et al., 2007).Entities:
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Year: 2007 PMID： 17956720 DOI： 10.1016/j.cell.2007.10.005
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 66.850