Literature DB >> 17956304

P2X(7) receptor-mediated reactive oxygen and nitrogen species formation: from receptor to generators.

J Hewinson1, A B Mackenzie.   

Abstract

RONS (reactive oxygen and nitrogen species) have traditionally been perceived to be detrimental to the physiology of the cell, with reports citing mechanisms by which a range of proteins, lipids and DNA are damaged. Consequently, their action has been attributed to many pathologies and the aging process. Opposing these actions are the protective functions held by RONS, as highlighted in microbial destruction, and their role as important cellular signalling molecules. The present paper will focus on the newly emerging field of P2X(7)R (P2X(7) receptor)-induced RONS generation and the current understanding of the signalling pathways from receptor to RONS generators.

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Year:  2007        PMID： 17956304     DOI： 10.1042/BST0351168

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  25 in total

1.  Activation of P2X receptors induces apoptosis in human retinal pigment epithelium.

Authors:  Dongli Yang; Susan G Elner; Andrea J Clark; Bret A Hughes; Howard R Petty; Victor M Elner
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-03-18       Impact factor: 4.799

2.  Brilliant Blue G, But Not Fenofibrate, Treatment Reverts Hemiparkinsonian Behavior and Restores Dopamine Levels in an Animal Model of Parkinson's Disease.

Authors:  Enéas G Ferrazoli; Héllio D N de Souza; Isis C Nascimento; Ágatha Oliveira-Giacomelli; Telma T Schwindt; Luiz R Britto; Henning Ulrich
Journal:  Cell Transplant       Date:  2017-04-13       Impact factor: 4.064

Review 3.  Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteins.

Authors:  Stanko S Stojilkovic; Elías Leiva-Salcedo; Milos B Rokic; Claudio Coddou
Journal:  Antioxid Redox Signal       Date:  2013-09-25       Impact factor: 8.401

4.  C terminus of the P2X7 receptor: treasure hunting.

Authors:  Helio Miranda Costa-Junior; Flávia Sarmento Vieira; Robson Coutinho-Silva
Journal:  Purinergic Signal       Date:  2011-01-27       Impact factor: 3.765

5.  P2X7 Receptor Signaling Contributes to Sepsis-Associated Brain Dysfunction.

Authors:  Luiz Eduardo Baggio Savio; Mariana G Juste Andrade; Paola de Andrade Mello; Patrícia Teixeira Santana; Aline Cristina Abreu Moreira-Souza; Janaína Kolling; Aline Longoni; Linda Feldbrügge; Yan Wu; Angela T S Wyse; Simon C Robson; Robson Coutinho-Silva
Journal:  Mol Neurobiol       Date:  2016-10-11       Impact factor: 5.590

6.  P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice.

Authors:  Saurabh Chatterjee; Ritu Rana; Jean Corbett; Maria B Kadiiska; Joyce Goldstein; Ronald P Mason
Journal:  Free Radic Biol Med       Date:  2012-02-15       Impact factor: 7.376

7.  P2X7 receptor activation induces reactive oxygen species formation in erythroid cells.

Authors:  Bin Wang; Ronald Sluyter
Journal:  Purinergic Signal       Date:  2012-09-27       Impact factor: 3.765

8.  The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types.

Authors:  Ryan O Stevenson; Rosanne M Taylor; James S Wiley; Ronald Sluyter
Journal:  Purinergic Signal       Date:  2009-06-16       Impact factor: 3.765

9.  P2X7 receptor deletion attenuates oxidative stress and liver damage in sepsis.

Authors:  Robson Coutinho-Silva; Luiz Eduardo Baggio Savio; Maria Luciana Larrouyet-Sarto; Augusto Shuiti Tamura; Vinícius Santos Alves; Patrícia T Santana; Roberta Ciarlini-Magalhães; Thuany Prado Rangel; Cassiana Siebert; Josiane R Hartwig; Tiago Marcon Dos Santos; Angela T S Wyse; Christina Maeda Takiya
Journal:  Purinergic Signal       Date:  2020-10-22       Impact factor: 3.765

10.  Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking.

Authors:  Lisa Y Lenertz; Monica L Gavala; Lindsay M Hill; Paul J Bertics
Journal:  Purinergic Signal       Date:  2009-03-05       Impact factor: 3.765
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