Effects of Croton zehntneri aqueous extracts on some cholinergic- and dopaminergic-related behaviours of laboratory rodents.

The effects of aqueous Croton zehntneri leaf and branch extracts, orally administered, on some dopaminergic- and cholinergic-related behaviours were studied in rats and mice. The leaf extract did not modify apomorphine-induced stereotypic behavior, haloperidol-induced catalepsy and active avoidance/escape responses. The branch extract reduced stereotypy but did not interfere with catalepsy and active avoidance behavior. Both extracts were capable of increasing the tremor induced by oxotremorine.