Literature DB >> 17954482

Clinical trials in paediatric haematology-oncology: are future successes threatened by the EU directive on the conduct of clinical trials?

Chris Mitchell1.   

Abstract

Mesh：

Year:  2007        PMID： 17954482      PMCID： PMC2083592          DOI： 10.1136/adc.2006.103713

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


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  24 in total

1.  The impact of the 'Clinical Trials' directive on the cost and conduct of non-commercial cancer trials in the UK.

Authors:  J Hearn; R Sullivan
Journal:  Eur J Cancer       Date:  2006-11-21       Impact factor: 9.162

2.  Harmful impact of EU clinical trials directive.

Authors:  Akseli Hemminki; Pirkko-Liisa Kellokumpu-Lehtinen
Journal:  BMJ       Date:  2006-03-04

3.  Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid.

Authors:  S FARBER; L K DIAMOND
Journal:  N Engl J Med       Date:  1948-06-03       Impact factor: 91.245

4.  Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial.

Authors:  C D Mitchell; S M Richards; S E Kinsey; J Lilleyman; A Vora; T O B Eden
Journal:  Br J Haematol       Date:  2005-06       Impact factor: 6.998

5.  Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster.

Authors:  M Schrappe; A Reiter; M Zimmermann; J Harbott; W D Ludwig; G Henze; H Gadner; E Odenwald; H Riehm
Journal:  Leukemia       Date:  2000-12       Impact factor: 11.528

6.  Immediate nephrectomy versus preoperative chemotherapy in the management of non-metastatic Wilms' tumour: results of a randomised trial (UKW3) by the UK Children's Cancer Study Group.

Authors:  Christopher Mitchell; Kathy Pritchard-Jones; Rosemary Shannon; Carolyn Hutton; Suzanne Stevens; David Machin; John Imeson; Anna Kelsey; Gordan M Vujanic; Peter Gornall; Jenny Walker; Roger Taylor; Pat Sartori; Juliet Hale; Gill Levitt; Boo Messahel; Helen Middleton; Richard Grundy; Jon Pritchard
Journal:  Eur J Cancer       Date:  2006-08-10       Impact factor: 9.162

7.  Failure of a new protocol to improve treatment results in paediatric lymphoblastic leukaemia: lessons from the UK Medical Research Council trials UKALL X and UKALL XI.

Authors:  Judith M Chessells; Georgina Harrison; Susan M Richards; Brenda E Gibson; Clifford C Bailey; Frank G H Hill; Ian M Hann
Journal:  Br J Haematol       Date:  2002-08       Impact factor: 6.998

8.  High dose melphalan in the treatment of advanced neuroblastoma: results of a randomised trial (ENSG-1) by the European Neuroblastoma Study Group.

Authors:  Jon Pritchard; Simon J Cotterill; Shirley M Germond; John Imeson; Jan de Kraker; David R Jones
Journal:  Pediatr Blood Cancer       Date:  2005-04       Impact factor: 3.167

9.  Toxicity and efficacy of 6-thioguanine versus 6-mercaptopurine in childhood lymphoblastic leukaemia: a randomised trial.

Authors:  Ajay Vora; Chris D Mitchell; Lynne Lennard; T O B Eden; Sally E Kinsey; John Lilleyman; Sue M Richards
Journal:  Lancet       Date:  2006-10-14       Impact factor: 79.321

10.  The treatment of Wilms' tumour: results of the United Kingdom Children's cancer study group (UKCCSG) second Wilms' tumour study.

Authors:  C Mitchell; P M Jones; A Kelsey; G M Vujanic; B Marsden; R Shannon; P Gornall; C Owens; R Taylor; J Imeson; H Middleton; J Pritchard
Journal:  Br J Cancer       Date:  2000-09       Impact factor: 7.640
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  2 in total

1.  Regulatory impediments jeopardizing the conduct of clinical trials in Europe funded by the National Institutes of Health.

Authors:  James D Neaton; Abdel Babiker; Mark Bohnhorst; Janet Darbyshire; Eileen Denning; Arnie Frishman; Jesper Grarup; Gregg Larson; Jens Lundgren
Journal:  Clin Trials       Date:  2010-08-20       Impact factor: 2.486

2.  The unintended consequences of clinical trials regulations.

Authors:  Alex D McMahon; David I Conway; Tom M Macdonald; Gordon T McInnes
Journal:  PLoS Med       Date:  2009-11-17       Impact factor: 11.069
  2 in total

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