Literature DB >> 17953956

When is elevated testosterone not testosterone? When it is an immunoassay interfering antibody.

Devon Ramaeker1, John Brannian, Kristi Egland, Kelly McCaul, Keith Hansen.   

Abstract

A discrepancy between clinical findings and a markedly elevated testosterone (T) level stimulated search to explain this inconsistency. The cause of the falsely elevated T level was determined to be heterophile antibodies from a polyclonal gammopathy in a subject with acute myelogenous leukemia.

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Year:  2007        PMID： 17953956     DOI： 10.1016/j.fertnstert.2007.07.1295

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  3 in total

1.  Using mass spectrometry to overcome the longstanding inaccuracy of a commercially-available clinical testosterone immunoassay.

Authors:  Junyan Shi; Rachel Bird; Michael W Schmeling; Andrew N Hoofnagle
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2021-10-04       Impact factor: 3.318

2.  Elevated testosterone on immunoassay in a patient with metastatic prostate cancer following androgen deprivation therapy and bilateral orchiectomy.

Authors:  Arjun Sarkar; Mohammad Rashid Siddiqui; Richard J Fantus; Maha Hussain; Joshua A Halpern; Ashley E Ross
Journal:  Urol Case Rep       Date:  2021-03-24

Review 3.  Hormone Immunoassay Interference: A 2021 Update.

Authors:  Khaldoun Ghazal; Severine Brabant; Dominique Prie; Marie-Liesse Piketty
Journal:  Ann Lab Med       Date:  2022-01-01       Impact factor: 3.464
  3 in total

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