OBJECTIVE: To describe the first reported case of a triplet pregnancy subsequent to the use of an aromatase inhibitor for ovulation induction. DESIGN: Case report. SETTING: Academic medical center. PATIENT(S): A 32-year-old female with polycystic ovary syndrome and primary infertility. INTERVENTION(S): Letrozole, 5 mg/day, on cycle days 2 to 6 for ovulation induction. MAIN OUTCOME MEASURE(S): Clinical pregnancy. RESULT(S): Viable triplet gestation. CONCLUSION(S): Use of an aromatase inhibitor for ovulation induction does not eliminate the risk for higher order multiple pregnancy.
OBJECTIVE: To describe the first reported case of a triplet pregnancy subsequent to the use of an aromatase inhibitor for ovulation induction. DESIGN: Case report. SETTING: Academic medical center. PATIENT(S): A 32-year-old female with polycystic ovary syndrome and primary infertility. INTERVENTION(S): Letrozole, 5 mg/day, on cycle days 2 to 6 for ovulation induction. MAIN OUTCOME MEASURE(S): Clinical pregnancy. RESULT(S): Viable triplet gestation. CONCLUSION(S): Use of an aromatase inhibitor for ovulation induction does not eliminate the risk for higher order multiple pregnancy.