Literature DB >> 17953175

[An outbreak of Q fever in The Netherlands--possible link to goats].

J E Van Steenbergen1, G Morroy, C A R Groot, F G H Ruikes, J H Marcelis, P Speelman.   

Abstract

In 2007, 73 cases of Q fever were identified through reports and retrospective analyses; the affected region extended from Tilburg in the southwest to Arnhem in the northeast. The infections arose in late spring, particularly in May and June. Several spontaneous abortions due to Q fever occurred on 4 dairy goat farms in the same region. The national incidence of spontaneous abortion due to Q fever was 6 cases in 2006 and 7 in 2007. Climatically, this southern region was extraordinarily dry during April 2007. All pregnant women from a small region with the highest incidence in northeast North Brabant were called for diagnostic testing. Infected patients were followed for symptoms and ultrasound was performed as indicated. A definitive source of the infection could not yet be identified. Favourable climatic conditions were suspected as the cause for the combination of widespread dissemination among goats and transmission to humans. Q fever is a zoonosis caused by Coxiella burnetti, a microorganism dispersed in great numbers in the area in which an infected animal gives birth. C. burnetti is particularly resistant to chemical and physical factors and can disperse by air across large distances under dry climatic conditions. Q fever should be considered in patients in The Netherlands who present with lower airway infection and, in rare cases, hepatitis. Reporting atypical clusters ofpneumonia to the Municipal Health Service (GGD) is advisable. The GGD maintains close contact with Animal Health Services, which is aware of current infectious animal diseases. Targeted investigation can identify the source of infection and eliminate it. Greater awareness can prevent delays in diagnosis and treatment and help identify chronic forms at an early stage or prevent them.

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Year:  2007        PMID: 17953175

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  17 in total

1.  Interlaboratory evaluation of different extraction and real-time PCR methods for detection of Coxiella burnetii DNA in serum.

Authors:  Jeroen J H C Tilburg; Willem J G Melchers; Annika M Pettersson; John W A Rossen; Mirjam H A Hermans; Erik J van Hannen; Marrigje H Nabuurs-Franssen; Maaike C de Vries; Alphons M Horrevorts; Corné H W Klaassen
Journal:  J Clin Microbiol       Date:  2010-09-08       Impact factor: 5.948

2.  Detection of Coxiella burnetii in complex matrices by using multiplex quantitative PCR during a major Q fever outbreak in The Netherlands.

Authors:  A de Bruin; A de Groot; L de Heer; J Bok; P R Wielinga; M Hamans; B J van Rotterdam; I Janse
Journal:  Appl Environ Microbiol       Date:  2011-07-22       Impact factor: 4.792

3.  Monitoring and Surveillance of Small Ruminant Health in The Netherlands.

Authors:  Eveline Dijkstra; Piet Vellema; Karianne Peterson; Carlijn Ter Bogt-Kappert; Reinie Dijkman; Liesbeth Harkema; Erik van Engelen; Marian Aalberts; Inge Santman-Berends; René van den Brom
Journal:  Pathogens       Date:  2022-05-31

4.  Syndromic surveillance for local outbreaks of lower-respiratory infections: would it work?

Authors:  Cees C van den Wijngaard; Liselotte van Asten; Wilfrid van Pelt; Gerda Doornbos; Nico J D Nagelkerke; Gé A Donker; Wim van der Hoek; Marion P G Koopmans
Journal:  PLoS One       Date:  2010-04-29       Impact factor: 3.240

5.  Cost-effectiveness of a screening strategy for Q fever among pregnant women in risk areas: a clustered randomized controlled trial.

Authors:  Janna M Munster; Alexander C A P Leenders; Wim van der Hoek; Peter M Schneeberger; Ariene Rietveld; Josien Riphagen-Dalhuisen; Ronald P Stolk; Carl J C M Hamilton; Esther de Vries; Jamie Meekelenkamp; Jerome R Lo-Ten-Foe; Albertus Timmer; Lolkje T W De Jong-van den Berg; Jan G Aarnoudse; Eelko Hak
Journal:  BMC Womens Health       Date:  2010-11-01       Impact factor: 2.809

6.  One-year follow-up of patients of the ongoing Dutch Q fever outbreak: clinical, serological and echocardiographic findings.

Authors:  G J M Limonard; M H Nabuurs-Franssen; G Weers-Pothoff; C Wijkmans; R Besselink; A M Horrevorts; P M Schneeberger; C A R Groot
Journal:  Infection       Date:  2010-09-21       Impact factor: 3.553

7.  Reduction of Coxiella burnetii prevalence by vaccination of goats and sheep, The Netherlands.

Authors:  Lenny Hogerwerf; René van den Brom; Hendrik I J Roest; Annemarie Bouma; Piet Vellema; Maarten Pieterse; Daan Dercksen; Mirjam Nielen
Journal:  Emerg Infect Dis       Date:  2011-03       Impact factor: 6.883

8.  Molecular epidemiology of Coxiella burnetii from ruminants in Q fever outbreak, the Netherlands.

Authors:  Hendrik I J Roest; Robin C Ruuls; Jeroen J H C Tilburg; Marrigje H Nabuurs-Franssen; Corne H W Klaassen; Piet Vellema; René van den Brom; Daan Dercksen; Willem Wouda; Marcel A H Spierenburg; Arco N van der Spek; Rob Buijs; Albert G de Boer; Peter Th J Willemsen; Fred G van Zijderveld
Journal:  Emerg Infect Dis       Date:  2011-04       Impact factor: 6.883

9.  Q fever in pregnant goats: pathogenesis and excretion of Coxiella burnetii.

Authors:  Hendrik-Jan Roest; Betty van Gelderen; Annemieke Dinkla; Dimitrios Frangoulidis; Fred van Zijderveld; Johanna Rebel; Lucien van Keulen
Journal:  PLoS One       Date:  2012-11-09       Impact factor: 3.240

10.  Seroepidemiological survey for Coxiella burnetii antibodies and associated risk factors in Dutch livestock veterinarians.

Authors:  René Van den Brom; Barbara Schimmer; Peter M Schneeberger; Wim A Swart; Wim van der Hoek; Piet Vellema
Journal:  PLoS One       Date:  2013-01-16       Impact factor: 3.240

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