OBJECTIVE: The aim of this study was to determine 1-year symptomatic outcome and its predictors in patients with FEP treated at 3 different publicly funded sites. METHOD: We evaluated FEP patients (n = 172) treated in specialized programs in 2 medium-sized centres and 1 large urban centre with an identical protocol for demographic variables, diagnosis, and duration of untreated psychosis (DUP) at entry, and positive, negative, and general psychopathology symptoms at entry, 6 months, and 1 year. We used a mixed model analysis of variance, with time and centre and interaction between time and centre as fixed effects and sex and DUP as covariates, to analyze data. RESULTS: A significant effect of time and time x centre interaction on positive, negative, and general symptom outcome was shown after controlling for ethnicity, education, and diagnosis. Patients showed significantly better outcome on all dimensions of symptoms in the 2 medium-sized centres, compared with the 1 large urban centre. Sex had a significant effect on negative and general symptoms, while DUP had no effect on any outcome measure. CONCLUSIONS: Similarly enriched EI services may produce different outcomes, even within a relatively homogeneous mental health system.
OBJECTIVE: The aim of this study was to determine 1-year symptomatic outcome and its predictors in patients with FEP treated at 3 different publicly funded sites. METHOD: We evaluated FEP patients (n = 172) treated in specialized programs in 2 medium-sized centres and 1 large urban centre with an identical protocol for demographic variables, diagnosis, and duration of untreated psychosis (DUP) at entry, and positive, negative, and general psychopathology symptoms at entry, 6 months, and 1 year. We used a mixed model analysis of variance, with time and centre and interaction between time and centre as fixed effects and sex and DUP as covariates, to analyze data. RESULTS: A significant effect of time and time x centre interaction on positive, negative, and general symptom outcome was shown after controlling for ethnicity, education, and diagnosis. Patients showed significantly better outcome on all dimensions of symptoms in the 2 medium-sized centres, compared with the 1 large urban centre. Sex had a significant effect on negative and general symptoms, while DUP had no effect on any outcome measure. CONCLUSIONS: Similarly enriched EI services may produce different outcomes, even within a relatively homogeneous mental health system.
Authors: Philipp S Baumann; Julien Elowe; Nadir Mebdouhi; Alessandra Solida; Philippe Conus Journal: Can J Psychiatry Date: 2017-05-30 Impact factor: 4.356
Authors: Stephanie R Penney; Aaron Prosser; Teresa Grimbos; Padraig Darby; Alexander I F Simpson Journal: Can J Psychiatry Date: 2017-10-23 Impact factor: 4.356
Authors: Michael T Compton; Sandra M Goulding; Claire E Ramsay; Jean Addington; Cheryl Corcoran; Elaine F Walker Journal: Clin Neuropsychiatry Date: 2008-12
Authors: Suzanne Archie; Lena Palaniyappan; Andrew T Olagunju; Natasha Johnson; Nicole Kozloff; Elham Sadeh; Andrea Bardell; Alexandra Baines; Kelly K Anderson; Oyedeji Ayonrinde; Manuela Ferrari Journal: JMIR Res Protoc Date: 2022-05-20
Authors: Nicole Kozloff; George Foussias; Janet Durbin; Sanjeev Sockalingam; Jean Addington; Donald Addington; Augustina Ampofo; Kelly K Anderson; Melanie Barwick; Sarah Bromley; Jasmyn E A Cunningham; Simone Dahrouge; Lillian Duda; Catherine Ford; Sheila Gallagher; John D Haltigan; Joanna Henderson; Alexia Jaouich; Dielle Miranda; Patrick Mitchell; Josette Morin; Claire de Oliveira; Valerie Primeau; Eva Serhal; Sophie Soklaridis; Diana Urajnik; Krista Whittard; Juveria Zaheer; Paul Kurdyak; Aristotle N Voineskos Journal: BMJ Open Date: 2020-06-03 Impact factor: 2.692