Ran Hong1, Sung-Chul Lim, Hyuk Jung. 1. Department of Pathology, College of Medicine, Chosun University Hospital, Dong-Gu, Gwangju, South Korea.
Abstract
BACKGROUND: A liposarcoma is the most frequent soft tissue sarcoma found in adults, however, a liposarcoma arising in uterus is extremely rare. Indeed, a liposarcoma coexistent with a leiomyoma is even rarer and there is only one case has been reported in the English literature to date. CASE: We describe a case of the uterine liposarcoma arising in a leiomyoma in 48-year-old woman who presented with dysmenorrhea, brownish vaginal discharge, and a rapidly enlarging lower abdominal mass. The tumor emerged from the lower segment of the endometrium and filled the endometrial cavity as a polypoid lesion. The authors of this study documented the adipocyte origin of the tumor with immunohistochemical and electron microscopical studies, the available literature was reviewed and the possible histogenesis was discussed. CONCLUSION: We herein report a case of very rare primary liposarcoma arising in a submucosal uterine leiomyoma.
BACKGROUND: A liposarcoma is the most frequent soft tissue sarcoma found in adults, however, a liposarcoma arising in uterus is extremely rare. Indeed, a liposarcoma coexistent with a leiomyoma is even rarer and there is only one case has been reported in the English literature to date. CASE: We describe a case of the uterine liposarcoma arising in a leiomyoma in 48-year-old woman who presented with dysmenorrhea, brownish vaginal discharge, and a rapidly enlarging lower abdominal mass. The tumor emerged from the lower segment of the endometrium and filled the endometrial cavity as a polypoid lesion. The authors of this study documented the adipocyte origin of the tumor with immunohistochemical and electron microscopical studies, the available literature was reviewed and the possible histogenesis was discussed. CONCLUSION: We herein report a case of very rare primary liposarcoma arising in a submucosal uterine leiomyoma.
Authors: Mehmet Kefeli; Sancar Baris; Oguz Aydin; Levent Yıldız; Seda Yamak; Bedri Kandemir Journal: Ann Saudi Med Date: 2012 Sep-Oct Impact factor: 1.526