OBJECTIVES: To estimate the disease burden attributable to being underweight as an indicator of undernutrition in children under 5 years of age and in pregnant women for the year 2000. DESIGN: World Health Organization comparative risk assessment (CRA) methodology was followed. The 1999 National Food Consumption Survey prevalence of underweight classified in three low weight-for-age categories was compared with standard growth charts to estimate population-attributable fractions for mortality and morbidity outcomes, based on increased risk for each category and applied to revised burden of disease estimates for South Africa in 2000. Maternal underweight, leading to an increased risk of intra-uterine growth retardation and further risk of low birth weight (LBW), was also assessed using the approach adopted by the global assessment. Monte Carlo simulation-modeling techniques were used for the uncertainty analysis. SETTING: South Africa. SUBJECTS: Children under 5 years of age and pregnant women. OUTCOME MEASURES: Mortality and disability-adjusted life years (DALYs) from protein- energy malnutrition and a fraction of those from diarrhoeal disease, pneumonia, malaria, other non- HIV/AIDS infectious and parasitic conditions in children aged 0 - 4 years, and LBW. RESULTS: Among children under 5 years, 11.8% were underweight. In the same age group, 11,808 deaths (95% uncertainty interval 11,100 - 12,642) or 12.3% (95% uncertainty interval 11.5 - 13.1%) were attributable to being underweight. Protein-energy malnutrition contributed 44.7% and diarrhoeal disease 29.6% of the total attributable burden. Childhood and maternal underweight accounted for 2.7% (95% uncertainty interval 2.6 - 2.9%) of all DALYs in South Africa in 2000 and 10.8% (95% uncertainty interval 10.2 - 11.5%) of DALYs in children under 5. CONCLUSIONS: The study shows that reduction of the occurrence of underweight would have a substantial impact on child mortality, and also highlights the need to monitor this important indicator of child health.
OBJECTIVES: To estimate the disease burden attributable to being underweight as an indicator of undernutrition in children under 5 years of age and in pregnant women for the year 2000. DESIGN: World Health Organization comparative risk assessment (CRA) methodology was followed. The 1999 National Food Consumption Survey prevalence of underweight classified in three low weight-for-age categories was compared with standard growth charts to estimate population-attributable fractions for mortality and morbidity outcomes, based on increased risk for each category and applied to revised burden of disease estimates for South Africa in 2000. Maternal underweight, leading to an increased risk of intra-uterine growth retardation and further risk of low birth weight (LBW), was also assessed using the approach adopted by the global assessment. Monte Carlo simulation-modeling techniques were used for the uncertainty analysis. SETTING: South Africa. SUBJECTS:Children under 5 years of age and pregnant women. OUTCOME MEASURES: Mortality and disability-adjusted life years (DALYs) from protein- energy malnutrition and a fraction of those from diarrhoeal disease, pneumonia, malaria, other non- HIV/AIDS infectious and parasitic conditions in children aged 0 - 4 years, and LBW. RESULTS: Among children under 5 years, 11.8% were underweight. In the same age group, 11,808 deaths (95% uncertainty interval 11,100 - 12,642) or 12.3% (95% uncertainty interval 11.5 - 13.1%) were attributable to being underweight. Protein-energy malnutrition contributed 44.7% and diarrhoeal disease 29.6% of the total attributable burden. Childhood and maternal underweight accounted for 2.7% (95% uncertainty interval 2.6 - 2.9%) of all DALYs in South Africa in 2000 and 10.8% (95% uncertainty interval 10.2 - 11.5%) of DALYs in children under 5. CONCLUSIONS: The study shows that reduction of the occurrence of underweight would have a substantial impact on child mortality, and also highlights the need to monitor this important indicator of child health.
Authors: Amina Abubakar; Fons Van de Vijver; Anneloes Van Baar; Leonard Mbonani; Raphael Kalu; Charles Newton; Penny Holding Journal: Early Hum Dev Date: 2008-05-21 Impact factor: 2.079
Authors: Lora L Sabin; Anna B Knapp; William B MacLeod; Grace Phiri-Mazala; Joshua Kasimba; Davidson H Hamer; Christopher J Gill Journal: PLoS One Date: 2012-04-24 Impact factor: 3.240
Authors: Nyaguara O Amek; Frank O Odhiambo; Sammy Khagayi; Hellen Moige; Gordon Orwa; Mary J Hamel; Annemieke Van Eijk; John Vulule; Laurence Slutsker; Kayla F Laserson Journal: Glob Health Action Date: 2014-10-29 Impact factor: 2.640
Authors: Jahit Sacarlal; Ariel Q Nhacolo; Betuel Sigaúque; Delino A Nhalungo; Fatima Abacassamo; Charfudin N Sacoor; Pedro Aide; Sonia Machevo; Tacilta Nhampossa; Eusébio V Macete; Quique Bassat; Catarina David; Azucena Bardají; Emili Letang; Francisco Saúte; John J Aponte; Ricardo Thompson; Pedro L Alonso Journal: BMC Public Health Date: 2009-02-24 Impact factor: 3.295