Literature DB >> 1795172

In vitro contraction test for malignant hyperthermia in patients with unexplained recurrent rhabdomyolysis.

P J Poels1, E M Joosten, R C Sengers, A M Stadhouders, J H Veerkamp, A A Benders.   

Abstract

A few cases of non-anaesthetic-induced rhabdomyolysis in humans, predisposed to malignant hyperthermia (MH), have been described in literature. We studied a group of 6 consecutive patients with unexplained and recurrent attacks of rhabdomyolysis with the test used to determine susceptibility to MH, the in vitro contraction test (IVCT). The results of the IVCT showed 5 of these 6 patients to be MH susceptible. In cultured muscle cells from one of these patients a disturbed calcium homeostasis could be demonstrated. The relation between MH and recurrent rhabdomyolysis is discussed.

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Year:  1991        PMID: 1795172     DOI: 10.1016/0022-510x(91)90120-v

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  4 in total

1.  Ryanodine receptor gene point mutation and malignant hyperthermia susceptibility.

Authors:  I Moroni; E F Gonano; G P Comi; V Tegazzin; A Prelle; A Bordoni; N Bresolin; G Scarlato
Journal:  J Neurol       Date:  1995-02       Impact factor: 4.849

Review 2.  [Malignant hyperthermia].

Authors:  Fritz Zimprich; Hans Georg Kress; Josef Zeitlhofer
Journal:  Wien Klin Wochenschr       Date:  2003-09-15       Impact factor: 1.704

3.  Elevated myoplasmic calcium in exercise-induced equine rhabdomyolysis.

Authors:  J R López; N Linares; G Cordovez; A Terzic
Journal:  Pflugers Arch       Date:  1995-06       Impact factor: 3.657

Review 4.  Exercise-induced rhabdomyolysis and stress-induced malignant hyperthermia events, association with malignant hyperthermia susceptibility, and RYR1 gene sequence variations.

Authors:  Antonella Carsana
Journal:  ScientificWorldJournal       Date:  2013-02-10
  4 in total

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