Michel J A M van Putten1, Maurice H P M van Putten. 1. Department of Neurology and Clinical Neurophysiology, Medisch Spectrum Twente, 7500 KA, Enschede, The Netherlands. m.vanputten@mailcss.com
Abstract
OBJECTIVE: We study burst-like patterns of epileptiform discharges in non-convulsive status epilepticus (SE). METHODS: Epileptiform burst-like transients were identified by estimating the amplitude envelope of the EEG signal, and recurrence and similarities were identified by pairwise matching in the time-domain. RESULTS: We identified similarities in the onset of a significant fraction of the epileptiform bursts, and a bimodal distribution of the burst durations. CONCLUSIONS: Bursts of epileptiform discharges during a non-convulsive SE are manifestations of multiple patterns of recurring brain states. SIGNIFICANCE: Quantitative description of ictal phenomena in epilepsy and status epilepticus adds to the knowledge of abnormal brain behavior and may assist in improved patient care.
OBJECTIVE: We study burst-like patterns of epileptiform discharges in non-convulsive status epilepticus (SE). METHODS:Epileptiform burst-like transients were identified by estimating the amplitude envelope of the EEG signal, and recurrence and similarities were identified by pairwise matching in the time-domain. RESULTS: We identified similarities in the onset of a significant fraction of the epileptiform bursts, and a bimodal distribution of the burst durations. CONCLUSIONS: Bursts of epileptiform discharges during a non-convulsive SE are manifestations of multiple patterns of recurring brain states. SIGNIFICANCE: Quantitative description of ictal phenomena in epilepsy and status epilepticus adds to the knowledge of abnormal brain behavior and may assist in improved patient care.