| Literature DB >> 17948167 |
Witoon Youngsa-ad1, Nattaya Ngamrojanavanich, Chulabhorn Mahidol, Somsak Ruchirawat, Hunsa Prawat, Prasat Kittakoop.
Abstract
Two new clerodane diterpenes, methyl 15,16-epoxy-3,13(16),14- ENT-clerodatrien-18,19-olide-17-carboxylate ( 1) and dimethyl 15,16-epoxy-12-oxo-3,13(16),14- ENT-clerodatriene-17,18-dicarboxylate ( 2), together with seven known compounds ( 3 - 9), were isolated from the roots of Croton oblongifolius. The isolated compounds showed only mild cytotoxic activity against HuCCA-1, KB, HeLa, MDA-MB231, and T47D cell lines with IC (50) values ranging from 10 to 50 microg/mL.Entities:
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Year: 2007 PMID： 17948167 DOI： 10.1055/s-2007-990247
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352