Bo-Guang Fan1. 1. Department of Surgery, Wenzhou Medical College, Taizhou Hospital, Zhejiang, China. fanboguang@gmail.com
Abstract
BACKGROUND: Many patients with advanced cancers have associated gastrointestinal (GI) obstruction. Parenteral nutrition (PN) is indicated in patients with a dysfunctional GI tract, but the role of PN in patients' survival is still controversial. The present study was retrospectively conducted to verify if there are any long-term survivors living for more than 1 year after initiation of PN without food or drink in patients with malignant GI tract obstruction resulting from advanced cancers. METHODS: One hundred fifteen adult patients with malignant GI obstruction were identified over a 6-year period at a palliative-care setting. Their median age was 51 years (range, 31-74 years), and 62 (54%) were women and 53 men (46%). All selected patients had malignant GI tract obstruction and started PN treatment after cessation of energy intake to time of death. Survival expectancy as a criterion was analyzed in all patients. RESULTS: The median time from initiation of PN to death was 6.5 months. Eleven patients survived >or=1 year and 2 patients have been alive for almost 4 years later after cessation of energy intake. CONCLUSIONS: PN can be expected to obtain a longer survival for the patient with GI tract obstruction caused by advanced cancer.
BACKGROUND: Many patients with advanced cancers have associated gastrointestinal (GI) obstruction. Parenteral nutrition (PN) is indicated in patients with a dysfunctional GI tract, but the role of PN in patients' survival is still controversial. The present study was retrospectively conducted to verify if there are any long-term survivors living for more than 1 year after initiation of PN without food or drink in patients with malignant GI tract obstruction resulting from advanced cancers. METHODS: One hundred fifteen adult patients with malignant GI obstruction were identified over a 6-year period at a palliative-care setting. Their median age was 51 years (range, 31-74 years), and 62 (54%) were women and 53 men (46%). All selected patients had malignant GI tract obstruction and started PN treatment after cessation of energy intake to time of death. Survival expectancy as a criterion was analyzed in all patients. RESULTS: The median time from initiation of PN to death was 6.5 months. Eleven patients survived >or=1 year and 2 patients have been alive for almost 4 years later after cessation of energy intake. CONCLUSIONS: PN can be expected to obtain a longer survival for the patient with GI tract obstruction caused by advanced cancer.
Authors: Anne Marie Sowerbutts; Simon Lal; Jana Sremanakova; Andrew Clamp; Chris Todd; Gordon C Jayson; Antje Teubner; Anne-Marie Raftery; Eileen J Sutton; Lisa Hardy; Sorrel Burden Journal: Cochrane Database Syst Rev Date: 2018-08-10
Authors: Mira Dreesen; Veerle Foulon; Martin Hiele; Kris Vanhaecht; Lutgart De Pourcq; Loris Pironi; André Van Gossum; Jann Arends; Cristina Cuerda; Paul Thul; Frederico Bozzetti; Ludo Willems Journal: Support Care Cancer Date: 2012-12-11 Impact factor: 3.603
Authors: Yeh Chen Lee; Nazlin Jivraj; Catherine O'Brien; Tanya Chawla; Eran Shlomovitz; Sarah Buchanan; Jenny Lau; Jennifer Croke; Johane P Allard; Preeti Dhar; Stephane Laframboise; Sarah E Ferguson; Neesha Dhani; Marcus Butler; Pamela Ng; Terri Stuart-McEwan; Pamela Savage; Lisa Tinker; Amit M Oza; Stephanie Lheureux Journal: Obstet Gynecol Int Date: 2018-05-17