| Literature DB >> 17947083 |
Sandeep P Nair1, J Chris Sackellares, Deng-Shan Shiau, Wendy M Norman, Linda K Dance, Panos M Pardalos, Jose C Principe, Paul R Carney.
Abstract
Progressive preictal dynamical convergence and postictal divergence of dynamical EEG descriptors among brain regions has been reported in human temporal lobe epilepsy (TLE) and in a rodent model of TLE. There are also reports of anticonvulsant effects of high frequency stimulation of the hippocampus in humans. We postulate that this anticonvulsant effect is due to dynamical resetting by the electrical stimulation. The following study investigated the effects of acute hippocampal electrical stimulation on dynamical transitions in the brain of a spontaneously seizing animal model of TLE to test the hypothesis of divergence in dynamical values by electrical stimulation of the hippocampus.Entities:
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Year: 2006 PMID： 17947083 DOI： 10.1109/IEMBS.2006.260830
Source DB: PubMed Journal: Conf Proc IEEE Eng Med Biol Soc ISSN： 1557-170X