Literature DB >> 17946364

Designing a planar vector field to investigate the role of a slow variable in an enhanced mean-field model during general anesthesia.

Behnam Molaee-Ardekani1, Mohammad-Bagher Shamsollahi, Lotfi Senhadji, Bijan Vosoughi-Vahdat, Eric Wodey.   

Abstract

Local mean-field models (MFMs) describe regional brain activities by some connected differential equations. In an overall view, constituting variables of these differential equations can be divided to very fast, fast and slow variables. In this article we propose a method that can be used to determine role of a slow variable in behavior of MFMs. Very fast variables can be adiabatically removed from the equations. Isoclines of fast and slow variables and their corresponding vector field can provide valuable information about model behavior and role of the slow variable in it. The vector field of our interested MFM that is an enhanced MFM designed specially for general anesthesia, is a 3D field (one slow and two fast variables) and it is not so convenient for visually inspecting the role of the slow variable in this model. To afford this problem we design a 2D (planar) vector filed that only considers the slow variable and one of the fast variables.

Mesh:

Substances:

Year:  2006        PMID: 17946364      PMCID: PMC2064971          DOI: 10.1109/IEMBS.2006.260801

Source DB:  PubMed          Journal:  Conf Proc IEEE Eng Med Biol Soc        ISSN: 1557-170X


  4 in total

1.  Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network model.

Authors:  Albert Compte; Maria V Sanchez-Vives; David A McCormick; Xiao-Jing Wang
Journal:  J Neurophysiol       Date:  2003-01-15       Impact factor: 2.714

Review 2.  Modelling general anaesthesia as a first-order phase transition in the cortex.

Authors:  Moira L Steyn-Ross; D A Steyn-Ross; J W Sleigh
Journal:  Prog Biophys Mol Biol       Date:  2004 Jun-Jul       Impact factor: 3.667

3.  Modeling the effects of anesthesia on the electroencephalogram.

Authors:  I Bojak; D T J Liley
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2005-04-04

4.  Extracellular calcium fluctuations and intracellular potentials in the cortex during the slow sleep oscillation.

Authors:  M Massimini; F Amzica
Journal:  J Neurophysiol       Date:  2001-03       Impact factor: 2.714

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.