| Literature DB >> 17945208 |
Wei Li1, Zaozao Qiu, Yibing Wang, Yichun Zhang, Ming Li, Jia Yu, Lihong Zhang, Ziyan Zhu, Biao Yu.
Abstract
Dioscin derivatives (1-12) with a variety of substitutions at the 6'-OH of the chacotriosyl residue and the 3',6'-anhydrosaponin derivatives (26, 30, and 32) were synthesized. All these derivatives showed much lower cytotoxicity than that of the parent dioscin, while their hemolytic activities were partially retained depending on the various 6'-O-substitutions.Entities:
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Year: 2007 PMID： 17945208 DOI： 10.1016/j.carres.2007.09.004
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104