Literature DB >> 1794422

In vitro corneal pathogenicity of Acanthamoeba.

D F Larkin1, M Berry, D L Easty.   

Abstract

The comparative cytopathic effects of a keratitis and an environmental isolate of Acanthamoeba were studied on confluent monolayers of human and rabbit corneal cells grown in culture. The presence of cells in culture induced excystment of amoebae to the active trophozoite form. Total destruction of cell monolayers was observed to be similar for both isolates, and dependent on incubation time and amoebic concentration. The relevance of these findings to human and experimental Acanthamoeba keratitis is discussed.

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Year:  1991        PMID： 1794422     DOI： 10.1038/eye.1991.98

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN： 0950-222X            Impact factor:   3.775


  9 in total

1.  Biochemical characterization and functional studies of Acanthamoeba mannose-binding protein.

Authors:  Marco Garate; Ibis Cubillos; Jeffrey Marchant; Noorjahan Panjwani
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

2.  Pathogenesis of acanthamoebic keratitis: hypothesis based on a histological analysis of 30 cases.

Authors:  A Garner
Journal:  Br J Ophthalmol       Date:  1993-06       Impact factor: 4.638

3.  By releasing ADP, Acanthamoeba castellanii causes an increase in the cytosolic free calcium concentration and apoptosis in wish cells.

Authors:  A Mattana; M G Tozzi; M Costa; G Delogu; P L Fiori; P Cappuccinelli
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

4.  Evaluation of the in vitro activity of commercially available moxifloxacin and voriconazole eye-drops against clinical strains of Acanthamoeba.

Authors:  C M Martín-Navarro; A López-Arencibia; F Arnalich-Montiel; B Valladares; J E Piñero; J Lorenzo-Morales
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2013-05-19       Impact factor: 3.117

5.  Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment.

Authors:  Weiyun Shi; Mingna Liu; Hua Gao; Suxia Li; Lixin Xie
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2009-05-09       Impact factor: 3.117

Review 6.  Acanthamoeba spp. as agents of disease in humans.

Authors:  Francine Marciano-Cabral; Guy Cabral
Journal:  Clin Microbiol Rev       Date:  2003-04       Impact factor: 26.132

7.  Apoptosis as a mechanism of cytolysis of tumor cells by a pathogenic free-living amoeba.

Authors:  H Alizadeh; M S Pidherney; J P McCulley; J Y Niederkorn
Journal:  Infect Immun       Date:  1994-04       Impact factor: 3.441

8.  Pathogenic strains of Acanthamoeba are recognized by TLR4 and initiated inflammatory responses in the cornea.

Authors:  Hassan Alizadeh; Trivendra Tripathi; Mahshid Abdi; Ashley Dawn Smith
Journal:  PLoS One       Date:  2014-03-14       Impact factor: 3.240

9.  Acanthamoeba-mediated cytopathic effect correlates with MBP and AhLBP mRNA expression.

Authors:  Sook-Luan Ng; Anisah Nordin; Norzana Abd Ghafar; Yusof Suboh; Noraina Ab Rahim; Kien-Hui Chua
Journal:  Parasit Vectors       Date:  2017-12-28       Impact factor: 3.876
  9 in total

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