OBJECTIVE: To assess the long-term risk of developing permanent AF in relation to the signal-averaged P wave duration (SAPWD) and clinical and echocardiographic characteristics. DESIGN: In an observational study design we studied 131 patients with earlier ECG-documented AF and successfully restored sinus rhythm attending a long-term, follow-up visit at hospital or at home. Established permanent AF was examined in relation to primary clinical, echocardiographic, and electrophysiological parameters. RESULTS: Only prolonged SAPWD (p=0.006) was associated with an increased risk of development of permanent AF. The risk of permanent AF after 3 years follow-up was 0.72 with an SAPWD equal to 180 ms versus 0.39 with a normal SAPWD (130 ms). We found no prognostic effect of age, gender, dilated left atrium, long duration of AF history, or long duration of the most recent episode of AF. Co-existing hypertension reduced the risk of permanent AF; this could be explained by concomitant treatment with angiotensin-converting-enzyme-inhibitors. CONCLUSION: Prolonged SAPWD (a marker of atrial remodelling) appears to be a risk factor for long-term development of permanent AF.
OBJECTIVE: To assess the long-term risk of developing permanent AF in relation to the signal-averaged P wave duration (SAPWD) and clinical and echocardiographic characteristics. DESIGN: In an observational study design we studied 131 patients with earlier ECG-documented AF and successfully restored sinus rhythm attending a long-term, follow-up visit at hospital or at home. Established permanent AF was examined in relation to primary clinical, echocardiographic, and electrophysiological parameters. RESULTS: Only prolonged SAPWD (p=0.006) was associated with an increased risk of development of permanent AF. The risk of permanent AF after 3 years follow-up was 0.72 with an SAPWD equal to 180 ms versus 0.39 with a normal SAPWD (130 ms). We found no prognostic effect of age, gender, dilated left atrium, long duration of AF history, or long duration of the most recent episode of AF. Co-existing hypertension reduced the risk of permanent AF; this could be explained by concomitant treatment with angiotensin-converting-enzyme-inhibitors. CONCLUSION: Prolonged SAPWD (a marker of atrial remodelling) appears to be a risk factor for long-term development of permanent AF.
Authors: Fariha Sadiq Ali; Andres Enriquez; Diego Conde; Damian Redfearn; Kevin Michael; Christopher Simpson; Hoshiar Abdollah; Antoni Bayés de Luna; Wilma Hopman; Adrian Baranchuk Journal: Ann Noninvasive Electrocardiol Date: 2015-02-02 Impact factor: 1.468
Authors: Katerina Pizzuto; Henry L Averns; Adrian Baranchuk; Hoshiar Abdollah; Kevin A Michael; Christopher Simpson; Damian P Redfearn Journal: Ann Noninvasive Electrocardiol Date: 2013-09-24 Impact factor: 1.468
Authors: Jelena Kornej; Jared W Magnani; Sarah R Preis; Elsayed Z Soliman; Ludovic Trinquart; Darae Ko; Emelia J Benjamin; Honghuang Lin Journal: Heart Rhythm Date: 2021-05-11 Impact factor: 6.343