Literature DB >> 17941643

Synthesis of a promising immunosuppressant: FR252921.

Dominique Amans1, Véronique Bellosta, Janine Cossy.   

Abstract

A concise and highly convergent synthesis of the promising immunosuppressant FR252921 was achieved by using optically active titanium complexes to control the configuration of the three stereogenic centers.

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Year:  2007        PMID： 17941643     DOI： 10.1021/ol702110k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  An enantioselective synthesis of the C3-C21 segment of the macrolide immunosuppressive agent FR252921.

Authors:  Arun K Ghosh; Samuel Rodriguez
Journal:  Tetrahedron Lett       Date:  2016-05-18       Impact factor: 2.415

2.  STILLE CROSS-COUPLING REACTIONS OF ARYL MESYLATES AND TOSYLATES USING A BIARYLPHOSPHINE BASED CATALYST SYSTEM.

Authors:  John R Naber; Brett P Fors; Xiaoxing Wu; Jonathon Gunn; Stephen L Buchwald
Journal:  Heterocycles       Date:  2010-02-26       Impact factor: 0.831

3.  A Domino 10-Step Total Synthesis of FR252921 and Its Analogues, Complex Macrocyclic Immunosuppressants.

Authors:  Yong Chen; Guilhem Coussanes; Caroline Souris; Paul Aillard; Dainis Kaldre; Kathrin Runggatscher; Stefan Kubicek; Giovanni Di Mauro; Boris Maryasin; Nuno Maulide
Journal:  J Am Chem Soc       Date:  2019-08-22       Impact factor: 16.383

Review 4.  Unconventional Macrocyclizations in Natural Product Synthesis.

Authors:  Iakovos Saridakis; Daniel Kaiser; Nuno Maulide
Journal:  ACS Cent Sci       Date:  2020-09-21       Impact factor: 14.553
  4 in total

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