Literature DB >> 1794027

Epidemiological considerations in the prevention of coronary heart disease among the elderly.

A Nissinen1, O Siitonen.   

Abstract

Coronary heart disease is a major health problem among the elderly, the importance of which increases with the rising proportion of old people. The significance of traditional cardiovascular risk factors has been documented in younger age groups, and it seems they are effective at least in 'young' elderly people (aged between 65 and 80 years), whereas their role is less well known in people over 80 years because other end-points such as stroke and cancer become increasingly important and coronary heart disease cannot be considered in isolation. Pharmacological treatment of hypertensive elderly patients can reduce the incidence of strokes significantly, but reduction of coronary heart disease incidence is less clear. There are many uncertainties relating to lipid-lowering medication in old people. Nonpharmacological means (modest lifestyle, healthy diet and regular exercise) are unlikely to be of harm in the prevention of coronary heart disease in the elderly.

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Year:  1991        PMID: 1794027     DOI: 10.2165/00002512-199101050-00005

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  20 in total

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Authors:  J Coope; T S Warrender
Journal:  Br Med J (Clin Res Ed)       Date:  1986-11-01

2.  Is elevated serum cholesterol level a risk factor for coronary heart disease in the elderly?

Authors:  R Benfante; D Reed
Journal:  JAMA       Date:  1990-01-19       Impact factor: 56.272

Review 3.  Review of primary prevention trials of coronary heart disease.

Authors:  J Stamler
Journal:  Acta Med Scand Suppl       Date:  1985

Review 4.  The uses of epidemiology in the study of the elderly. Report of a WHO Scientific Group on the Epidemiology of Aging.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  1984

5.  Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group.

Authors: 
Journal:  JAMA       Date:  1991-06-26       Impact factor: 56.272

6.  Risk factors for ischaemic heart disease: the prospective phase of the British Regional Heart Study.

Authors:  A G Shaper; S J Pocock; M Walker; A N Phillips; T P Whitehead; P W Macfarlane
Journal:  J Epidemiol Community Health       Date:  1985-09       Impact factor: 3.710

7.  International trends in cardiovascular diseases in the elderly.

Authors:  K Uemura
Journal:  Eur Heart J       Date:  1988-03       Impact factor: 29.983

8.  Risk factors for cardiovascular disease among 55 to 74 year-old Finnish men: a 10-year follow-up.

Authors:  A Nissinen; J Pekkanen; A Porath; S Punsar; M J Karvonen
Journal:  Ann Med       Date:  1989-06       Impact factor: 4.709

9.  Twenty-five-year mortality from coronary heart disease and its prediction in five cohorts of middle-aged men in Finland, The Netherlands, and Italy.

Authors:  A Menotti; A Keys; D Kromhout; A Nissinen; H Blackburn; F Fidanza; S Giampaoli; M J Karvonen; J Pekkanen; S Punsar
Journal:  Prev Med       Date:  1990-05       Impact factor: 4.018

10.  Proportional hazards analysis of risk factors for coronary heart disease in individuals aged 65 or older. The Framingham Heart Study.

Authors:  T Harris; E F Cook; W B Kannel; L Goldman
Journal:  J Am Geriatr Soc       Date:  1988-11       Impact factor: 5.562

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