Literature DB >> 17939720

Regioselective synthesis of asymmetrically substituted 2-quinoxalinol salen ligands.

Xianghong Wu1, Anne E V Gorden, Stephen A Tonks, Jonah Z Vilseck.   

Abstract

Diamino-2-quinoxalinols are reacted with salicylaldehyde derivatives to produce 2-quinoxalinol imines regioselectively as one isomer in good yield. Regioselectivity has been determined through the use of isotopic 15N labeling experiments. The 2-quinoxalinol imines may then be reacted without further purification with additional salicylaldehyde derivatives to yield asymmetrically substituted 2-quinoxalinol salens.

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Year:  2007        PMID: 17939720     DOI: 10.1021/jo701395w

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

Review 1.  15N labeling and analysis of 13C-15N and 1H-15N couplings in studies of the structures and chemical transformations of nitrogen heterocycles.

Authors:  Sergey L Deev; Igor A Khalymbadzha; Tatyana S Shestakova; Valery N Charushin; Oleg N Chupakhin
Journal:  RSC Adv       Date:  2019-08-28       Impact factor: 4.036

2.  PIDA-mediated intramolecular oxidative C-N bond formation for the direct synthesis of quinoxalines from enaminones.

Authors:  Hong Zhang; Jinhai Shen; Zhenhui Yang; Xiuling Cui
Journal:  RSC Adv       Date:  2019-03-07       Impact factor: 4.036

  2 in total

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