Literature DB >> 17939608

Use of acellular human dermal allograft for vaginoplasty in Mayer-Rokitansky-Küster-Hauser syndrome: a case report.

Wendy Kuohung1, Sharon R Thompson, Marc R Laufer.   

Abstract

BACKGROUND: Both autologous and synthetic tissue have been used to create a neovagina in women with Mayer-Rokitansky-Küster-Hauser syndrome. Despite reports on many different techniques, the ideal method of vaginoplasty has not been firmly established. CASE: A 33-year-old woman with Mayer-Rokitansky-Küster-Hauser syndrome had been unsuccessful in using vaginal dilators for the creation of a functional vagina with the Frank technique due to pain and vulvar lichen sclerosis. She thus elected to undergo vaginoplasty by a modified McIndoe procedure using acellular human dermal allograft material. Both the surgery and immediate postoperative course were uncomplicated. Vaginal apex stenosis resulted from inadequate dilatation in the weeks following surgery since the patient experienced pain with dilator use.
CONCLUSION: The use of dermal allograft material instead of a split-thickness autologous skin graft is a simple and less invasive method of constructing a neovagina. Due to the many potential advantages of this technique, further investigation is warranted to optimize long-term outcomes of vaginoplasty using this method.

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Year:  2007        PMID: 17939608

Source DB:  PubMed          Journal:  J Reprod Med        ISSN: 0024-7758            Impact factor:   0.142


  4 in total

1.  Restoration of vaginal anatomy after extensive posterior wall resection utilizing human acellular dermal matrix.

Authors:  Amit K Bhavsar; Kevin M Lin-Hurtubise; Charles S Dietrich
Journal:  Gynecol Oncol Rep       Date:  2016-01-27

2.  Role of progenitor cell producing normal vagina by metaplasia in laparoscopic peritoneal vaginoplasty.

Authors:  Pravin N Mhatre; Hemraj R Narkhede; P Amol Pawar; P Jyoti Mhatre; Das Dhanjit Kumar
Journal:  J Hum Reprod Sci       Date:  2016 Oct-Dec

Review 3.  Application of Acellular Dermal Matrix in Gynaecology-A Current Review.

Authors:  Kaja Skowronek; Wojciech Łabuś; Rafał Stojko; Diana Kitala; Marcin Sadłocha; Agnieszka Drosdzol-Cop
Journal:  J Clin Med       Date:  2022-07-12       Impact factor: 4.964

4.  Novel Technique of Vaginoplasty Developing Normal Vagina, Role of Stemness Markers and Translational Genes.

Authors:  Pravin Mhatre; Vikas Dighe; Dhanjit Kumar Das; Amol Pawar
Journal:  J Hum Reprod Sci       Date:  2020-12-28
  4 in total

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