Literature DB >> 17936805

Holmium laser treatment for low grade, low stage, noninvasive bladder cancer with local anesthesia and early instillation of mitomycin C.

Jorge Soler-Martínez1, Raúl Vozmediano-Chicharro, Pedro Morales-Jiménez, David Hernández-Alcaraz, Eloy Vivas-Vargas, Ildefonso Santos García-Vaquero, Víctor Baena-González.   

Abstract

PURPOSE: We evaluated the results of laser photocoagulation of recurrent low stage noninvasive bladder cancer.
MATERIALS AND METHODS: The study included 36 patients with a recurrent superficial papillary tumor within 1 year of endoscopic resection. Patients underwent laser photocoagulation of the recurrence under local anesthesia and sedation. They received early instillation of 40 mg mitomycin C and were discharged home without a catheter a few hours after the operation. Patients completed a visual analog scale to quantify the perceived level of pain, including 1--no pain to 10--maximum pain. Patients were reviewed after 3, 6 and 12 months to evaluate tumor recurrence.
RESULTS: The mean and median visual analog scale score was 3 points (range 1 to 10). No patient had urinary infection or a catheter at hospital discharge. The incidence of recurrence at 12 months was 25%, mainly in the first 15 cases.
CONCLUSIONS: Laser photocoagulation with local anesthesia and sedation is easy to perform and well tolerated. There were no complications and the recurrence rate was similar to that of transurethral resection, as calculated using the recurrence calculator of the 2006 guidelines on TaT1 (nonmuscle invasive) bladder cancer from the European Association of Urology.

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Year:  2007        PMID: 17936805     DOI: 10.1016/j.juro.2007.08.034

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  6 in total

Review 1.  [En bloc resection and vaporization techniques for the treatment of bladder cancer].

Authors:  J P Struck; A Karl; C Schwentner; T R W Herrmann; M W Kramer
Journal:  Urologe A       Date:  2018-06       Impact factor: 0.639

2.  Spatially controlled photothermal heating of bladder tissue through single-walled carbon nanohorns delivered with a fiberoptic microneedle device.

Authors:  R Lyle Hood; William F Carswell; Amanda Rodgers; Mehmet A Kosoglu; Marissa Nichole Rylander; David Grant; John L Robertson; Christopher G Rylander
Journal:  Lasers Med Sci       Date:  2012-10-04       Impact factor: 3.161

Review 3.  Current evidence for transurethral laser therapy of non-muscle invasive bladder cancer.

Authors:  Mario W Kramer; Thorsten Bach; Mathias Wolters; Florian Imkamp; Andreas J Gross; Markus A Kuczyk; Axel S Merseburger; Thomas R W Herrmann
Journal:  World J Urol       Date:  2011-05-05       Impact factor: 4.226

Review 4.  Current evidence of transurethral Ho:YAG and Tm:YAG treatment of bladder cancer: update 2014.

Authors:  Mario W Kramer; Mathias Wolters; Hannes Cash; Stephan Jutzi; Florian Imkamp; Markus A Kuczyk; Axel S Merseburger; Thomas R W Herrmann
Journal:  World J Urol       Date:  2014-06-17       Impact factor: 4.226

5.  Holmium laser transurethral resection of bladder tumor: Our experience.

Authors:  Nischith D'souza; Ashish Verma
Journal:  Urol Ann       Date:  2016 Oct-Dec

6.  Safety, feasibility, and quality of holmium laser en-bloc resection of nonmuscle invasive bladder tumors - A single-center experience.

Authors:  Pankaj N Maheshwari; Amandeep Manjeet Arora; Mahesh S Sane; Vivek Ganesh Jadhao
Journal:  Indian J Urol       Date:  2020-04-07
  6 in total

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