| Literature DB >> 17936357 |
Clarissa Bonafé Gaspar Ruas1, Cleoni Dos Santos Carvalho, Heloísa Sobreiro Selistre de Araújo, Evaldo Luiz Gaeta Espíndola, Marisa Narciso Fernandes.
Abstract
The oxidative stress biomarkers of exposure, such as reduced glutathione (GSH), activity of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) and the levels of lipid peroxidation (LPO), were measured in the blood of three cichlid fish (Oreochromis niloticus, Tilapia rendalli, and Geophagus brasiliensis) taken during two seasons from two sites, unpolluted and polluted by industrial effluents, to evaluate the effectiveness of these biomarkers in assessing the impact of water contamination. The LPO levels in the blood were higher in fish from the metal-contaminated site and the chronic exposure led to significant changes in GPx, CAT, and SOD activities in all three cichlid species. The considerable variation of responses in these cichlids to water contamination evidenced differences in sensitivity to the metal contamination and/or in the potential to respond to it highlighting the importance of using a set of related biomarkers to assess the impact of water contamination.Entities:
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Year: 2007 PMID： 17936357 DOI： 10.1016/j.ecoenv.2007.08.018
Source DB: PubMed Journal: Ecotoxicol Environ Saf ISSN： 0147-6513 Impact factor: 6.291