Literature DB >> 1793527

Regulation of IgE synthesis by cytokines.

J E de Vries1, J F Gauchat, G G Aversa, J Punnonen, H Gascan, H Yssel.   

Abstract

Considerable progress has been made in our understanding of the mechanisms underlying regulation of human IgE synthesis. Interleukin-4 induces IgE production specifically, but costimulatory signals provided by T cells are required. Other cytokines modulate interleukin-4-induced IgE synthesis. The roles of T cells and cytokines in regulating IgE switching are discussed.

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Year:  1991        PMID： 1793527     DOI： 10.1016/s0952-7915(05)80003-2

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  12 in total

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7.  Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

Authors:  J Punnonen; G Aversa; B G Cocks; A N McKenzie; S Menon; G Zurawski; R de Waal Malefyt; J E de Vries
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