BACKGROUND: To determine the diagnostic value of the clapping test, which has been proposed as a reliable measure to differentiate between progressive supranuclear palsy (where performance is impaired) and Parkinson's disease (where performance should be normal). METHODS: Our study group included a large cohort of consecutive outpatients including 44 patients with Parkinson's disease, 48 patients with various forms of atypical parkinsonism and 149 control subjects. All subjects performed the clapping test according to a standardized protocol. RESULTS: Clapping test performance was normal in all control subjects, and impaired in 63% of the patients with atypical parkinsonism. Unexpectedly, we also found an impaired clapping test in 29% of the patients with Parkinson's disease. CONCLUSION: Although the proportion with an abnormal clapping test was significantly higher in atypical parkinsonism, the clapping test did not discriminate well between Parkinson's disease and atypical parkinsonism.
BACKGROUND: To determine the diagnostic value of the clapping test, which has been proposed as a reliable measure to differentiate between progressive supranuclear palsy (where performance is impaired) and Parkinson's disease (where performance should be normal). METHODS: Our study group included a large cohort of consecutive outpatients including 44 patients with Parkinson's disease, 48 patients with various forms of atypical parkinsonism and 149 control subjects. All subjects performed the clapping test according to a standardized protocol. RESULTS: Clapping test performance was normal in all control subjects, and impaired in 63% of the patients with atypical parkinsonism. Unexpectedly, we also found an impaired clapping test in 29% of the patients with Parkinson's disease. CONCLUSION: Although the proportion with an abnormal clapping test was significantly higher in atypical parkinsonism, the clapping test did not discriminate well between Parkinson's disease and atypical parkinsonism.
Authors: Irene Litvan; Kailash P Bhatia; David J Burn; Christopher G Goetz; Anthony E Lang; Ian McKeith; Niall Quinn; Kapil D Sethi; Cliff Shults; Gregor K Wenning Journal: Mov Disord Date: 2003-05 Impact factor: 10.338
Authors: G C Román; T K Tatemichi; T Erkinjuntti; J L Cummings; J C Masdeu; J H Garcia; L Amaducci; J M Orgogozo; A Brun; A Hofman Journal: Neurology Date: 1993-02 Impact factor: 9.910
Authors: Sonja Schönecker; Franz Hell; Kai Bötzel; Elisabeth Wlasich; Nibal Ackl; Christine Süßmair; Markus Otto; Sarah Anderl-Straub; Albert Ludolph; Jan Kassubek; Hans-Jürgen Huppertz; Janine Diehl-Schmid; Lina Riedl; Carola Roßmeier; Klaus Fassbender; Epameinondas Lyros; Johannes Kornhuber; Timo Jan Oberstein; Klaus Fliessbach; Anja Schneider; Matthias L Schroeter; Johannes Prudlo; Martin Lauer; Holger Jahn; Johannes Levin; Adrian Danek Journal: J Neurol Date: 2018-12-01 Impact factor: 4.849
Authors: Anouk Gw van Norden; Karlijn F de Laat; Rob Ar Gons; Inge Wm van Uden; Ewoud J van Dijk; Lucas Jb van Oudheusden; Rianne Aj Esselink; Bastiaan R Bloem; Baziel Gm van Engelen; Machiel J Zwarts; Indira Tendolkar; Marcel G Olde-Rikkert; Maureen J van der Vlugt; Marcel P Zwiers; David G Norris; Frank-Erik de Leeuw Journal: BMC Neurol Date: 2011-02-28 Impact factor: 2.474