Literature DB >> 17934772

Resectability of pancreatic adenocarcinoma: assessment using multidetector-row computed tomography with multiplanar reformations.

Elena Manak1, Susanne Merkel, Peter Klein, Thomas Papadopoulos, Werner A Bautz, Ulrich Baum.   

Abstract

The purpose was to assess capabilities of the multidetector-row computed tomography (MDCT) with multiplanar reformations (MPR) for predicting of pancreatic adenocarcinoma resectability. Forty-eight patients deemed to have resectable pancreatic adenocarcinoma after assessment using biphasic MDCT with MPRs underwent surgery for potential tumor resection. Imaging findings were retrospectively evaluated for tumor resectability and correlated with surgical and pathological results. Curative resection was successful in 44 of 48 patients. The positive predictive value for tumor resectability made up 91% with four false-negative results. The reasons for unresectability were venous involvement (1), small liver metastases (2) and peritoneal involvement associated with small metastases to lymph nodes (1). MDCT yielded a negative predictive value of 99% (286 of 288 vessels) for detection of vascular invasion. Our results indicate the tendency towards improved prediction of resectability using MDCT compared to single-detector CT.

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Year:  2009        PMID: 17934772     DOI: 10.1007/s00261-007-9285-2

Source DB:  PubMed          Journal:  Abdom Imaging        ISSN: 0942-8925


  15 in total

1.  Computed tomography-based diagnostics might be insufficient in the determination of pancreatic cancer unresectability.

Authors:  Vyacheslav I Egorov; Roman V Petrov; Elena N Solodinina; Gregory G Karmazanovsky; Natalia S Starostina; Natalia A Kuruschkina
Journal:  World J Gastrointest Surg       Date:  2013-04-27

2.  Role of Multi Detector Computed Tomography (MDCT) in Preoperative Staging of Pancreatic Carcinoma.

Authors:  Soumil Singhal; Nirmal Kumar Prabhu; Pulkit Sethi; Srikanth Moorthy
Journal:  J Clin Diagn Res       Date:  2017-05-01

3.  State-of-the-art PET/CT of the pancreas: current role and emerging indications.

Authors:  Dushyant V Sahani; Pietro A Bonaffini; Onofrio A Catalano; Alexander R Guimaraes; Michael A Blake
Journal:  Radiographics       Date:  2012 Jul-Aug       Impact factor: 5.333

4.  Pancreatic adenocarcinoma: Outstanding problems.

Authors:  Olga P Zakharova; Grigory G Karmazanovsky; Viacheslav I Egorov
Journal:  World J Gastrointest Surg       Date:  2012-05-27

5.  Surgical strategies for restoring liver arterial perfusion in pancreatic resections.

Authors:  Martin de Santibañes; Fernando A Alvarez; Oscar M Mazza; Rodrigo Sanchez Claria; Fanny Rodriguez Santos; Claudio Brandi; Eduardo de Santibañes; Juan Pekolj
Journal:  Langenbecks Arch Surg       Date:  2016-01-06       Impact factor: 3.445

Review 6.  Imaging diagnosis of pancreatic cancer: a state-of-the-art review.

Authors:  Eun Sun Lee; Jeong Min Lee
Journal:  World J Gastroenterol       Date:  2014-06-28       Impact factor: 5.742

7.  Response evaluation following neoadjuvant treatment of pancreatic cancer patients.

Authors:  Chiara Tosolini; Christoph W Michalski; Jörg Kleeff
Journal:  World J Gastrointest Surg       Date:  2013-02-27

8.  CA724 is a novel factor for predicting the unresectability in pancreatic adenocarcinoma.

Authors:  Peng Liu; Yuan Zhu; Luying Liu
Journal:  Int J Clin Exp Pathol       Date:  2015-11-01

9.  The exploration of quantitative intra-tumoral metabolic heterogeneity in dual-time 18F-FDG PET/CT of pancreatic cancer.

Authors:  Guorong Jia; Jian Zhang; Rou Li; Jianhua Yan; Changjing Zuo
Journal:  Abdom Radiol (NY)       Date:  2021-04-18

10.  Preoperative prediction of curative surgery of perihilar cholangiocarcinoma by combination of endoscopic ultrasound and computed tomography.

Authors:  Sara Kammerer; Tobias Meister; Heiner Wolters; Matthias Lessing; Anna Hüsing; Dirk Domagk; Martin Floer; Christian Wilms; Hartmut Schmidt; Norbert Senninger; Gabriele Köhler; Hauke Sebastian Heinzow
Journal:  United European Gastroenterol J       Date:  2017-05-25       Impact factor: 4.623

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