Literature DB >> 17934703

[The older patient with malignant diseases].

C Buske1, W Hiddemann.   

Abstract

Most malignancies show a steep increase of incidence with growing age. Because of this age specific incidence and the general aging of the population in western industrial countries the number of elderly cancer patients continuously and rapidly increases. Despite this development elderly cancer patients are currently underrepresented in clinical trials. This is caused in part by the lack of a common definition of the elderly patient and by the fact that a part of the elderly patients suffers from co-morbidities, not allowing a more dose intense treatment in these patients. It is one of the key current challenges to compensate this deficit and to develop therapeutic concepts specifically for the elderly patients, taking the individual somatic, but also social situation and finally the quality and perspective of life of the elderly patient into account.

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Year:  2007        PMID: 17934703     DOI: 10.1007/s00108-007-1955-1

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  11 in total

1.  Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001.

Authors:  Lindsay M Morton; Sophia S Wang; Susan S Devesa; Patricia Hartge; Dennis D Weisenburger; Martha S Linet
Journal:  Blood       Date:  2005-09-08       Impact factor: 22.113

Review 2.  Treatment of older patients with AML.

Authors:  Thomas Büchner; Wolfgang E Berdel; Bernhard Wörmann; Claudia Schoch; Torsten Haferlach; Susanne Schnittger; Wolfgang Kern; Carlo Aul; Eva Lengfelder; Andrea Schumacher; Albrecht Reichle; Peter Staib; Leopold Balleisen; Hartmut Eimermacher; Andreas Grüneisen; Herbert Rasche; Maria Cristina Sauerland; Achim Heinecke; Rolf M Mesters; Hubert L Serve; Joachim Kienast; Wolfgang Hiddemann
Journal:  Crit Rev Oncol Hematol       Date:  2005-10-21       Impact factor: 6.312

3.  Underrepresentation of patients 65 years of age or older in cancer-treatment trials.

Authors:  L F Hutchins; J M Unger; J J Crowley; C A Coltman; K S Albain
Journal:  N Engl J Med       Date:  1999-12-30       Impact factor: 91.245

Review 4.  Never too old? Age should not be a barrier to enrollment in cancer clinical trials.

Authors:  Matti S Aapro; Claus-Henning Köhne; Harvey Jay Cohen; Martine Extermann
Journal:  Oncologist       Date:  2005-03

5.  Association of comorbidity with disability in older women: the Women's Health and Aging Study.

Authors:  L P Fried; K Bandeen-Roche; J D Kasper; J M Guralnik
Journal:  J Clin Epidemiol       Date:  1999-01       Impact factor: 6.437

Review 6.  Lymphoma in older patients.

Authors:  Catherine Thieblemont; Bertrand Coiffier
Journal:  J Clin Oncol       Date:  2007-05-10       Impact factor: 44.544

Review 7.  Cancer: a disease of the elderly.

Authors:  William B Ershler
Journal:  J Support Oncol       Date:  2003 Nov-Dec

8.  Are older French patients as willing as older American patients to undertake chemotherapy?

Authors:  Martine Extermann; Gilles Albrand; Hongbin Chen; Sylvie Zanetta; Ronald Schonwetter; Gilbert B Zulian; Alan Cantor; Jean-Pierre Droz
Journal:  J Clin Oncol       Date:  2003-07-21       Impact factor: 44.544

9.  Enrollment of older patients in cancer treatment trials in Canada: why is age a barrier?

Authors:  Karen W L Yee; Joseph L Pater; Lam Pho; Benny Zee; Lillian L Siu
Journal:  J Clin Oncol       Date:  2003-04-15       Impact factor: 44.544

10.  Barriers to clinical trial participation by older women with breast cancer.

Authors:  M Margaret Kemeny; Bercedis L Peterson; Alice B Kornblith; Hyman B Muss; Judith Wheeler; Ellis Levine; Nancy Bartlett; Gini Fleming; Harvey J Cohen
Journal:  J Clin Oncol       Date:  2003-06-15       Impact factor: 44.544

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  1 in total

1.  Perceived social support and associations with health-related quality of life in young versus older adult patients with haematological malignancies.

Authors:  Kristina Geue; Heide Götze; Michael Friedrich; Katja Leuteritz; Anja Mehnert-Theuerkauf; Annekathrin Sender; Yve Stöbel-Richter; Norbert Köhler
Journal:  Health Qual Life Outcomes       Date:  2019-08-22       Impact factor: 3.186

  1 in total

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