OBJECTIVE: Although ADHD medications are effective for the behavioral components of the disorder, little information exists concerning their effects on cognition, especially in community samples. METHOD: A cross-sectional study of ADHD patients treated with three different ADHD drugs was conducted. Patients' performance on a computerized neurocognitive screening battery was compared to untreated ADHD patients and normal controls (NML). A total of 177 ADHD patients aged 10 to 18, achieved a favorable response to one of the following medications: Adderall XR (AMP), atomoxetine (ATMX), and Concerta (MPH-OROS) compared to 95 untreated ADHD patients and 101 NML. RESULTS: Significant differences were detected between normals and untreated ADHD patients. Treated patients performed better than untreated patients but remained significantly impaired compared to normal subjects. CONCLUSION: Even with optimal treatment, based on parents' and teachers' opinions, subtle and not-so-subtle neurocognitive impairments persisted in the ADHD patients. Some ADHD patients may require additional educational assistance, even in the face of successful medication treatment.
OBJECTIVE: Although ADHD medications are effective for the behavioral components of the disorder, little information exists concerning their effects on cognition, especially in community samples. METHOD: A cross-sectional study of ADHDpatients treated with three different ADHD drugs was conducted. Patients' performance on a computerized neurocognitive screening battery was compared to untreated ADHDpatients and normal controls (NML). A total of 177 ADHDpatients aged 10 to 18, achieved a favorable response to one of the following medications: Adderall XR (AMP), atomoxetine (ATMX), and Concerta (MPH-OROS) compared to 95 untreated ADHDpatients and 101 NML. RESULTS: Significant differences were detected between normals and untreated ADHDpatients. Treated patients performed better than untreated patients but remained significantly impaired compared to normal subjects. CONCLUSION: Even with optimal treatment, based on parents' and teachers' opinions, subtle and not-so-subtle neurocognitive impairments persisted in the ADHDpatients. Some ADHDpatients may require additional educational assistance, even in the face of successful medication treatment.
Authors: Tracey W Tsang; Michael R Kohn; Daniel F Hermens; Simon D Clarke; C Richard Clark; Daryl Efron; Noel Cranswick; Chris Lamb; Leanne M Williams Journal: Trials Date: 2011-03-13 Impact factor: 2.279
Authors: Oliver Tucha; Lara Tucha; Gesa Kaumann; Sebastian König; Katharina M Lange; Dorota Stasik; Zoe Streather; Tobias Engelschalk; Klaus W Lange Journal: Atten Defic Hyperact Disord Date: 2011-05-20
Authors: Antonio Carlos Farias; Mara L Cordeiro; Erico Pg Felden; Tiago S Bara; Cássia R Benko; Daniele Coutinho; Leandra F Martins; Rosilda Tc Ferreira; James T McCracken Journal: Neuropsychiatr Dis Treat Date: 2017-07-06 Impact factor: 2.570
Authors: Anselm B M Fuermaier; Lara Tucha; Ben Lewis Evans; Janneke Koerts; Dick de Waard; Karel Brookhuis; Steffen Aschenbrenner; Johannes Thome; Klaus W Lange; Oliver Tucha Journal: J Neural Transm (Vienna) Date: 2015-09-29 Impact factor: 3.575