Literature DB >> 17933887

YhbO protects cells against multiple stresses.

Jad Abdallah1, Teresa Caldas, Fatoum Kthiri, Renée Kern, Gilbert Richarme.   

Abstract

YhbO is a member of the DJ-1/ThiJ/Pfp1 superfamily, which includes chaperones, peptidases, and the Parkinson's disease protein DJ-1. A yhbO-disrupted mutant of Escherichia coli is highly sensitive to oxidative, thermal, UV, and pH stresses, and the putative nucleophilic cysteine C104 of YhbO is required for stress resistance. These results suggest that YhbO affects a central process in stress management.

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Year:  2007        PMID: 17933887      PMCID: PMC2168597          DOI: 10.1128/JB.01208-07

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  30 in total

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  19 in total

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