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Literature DB >> 17932582

Coronary vasoregulation in health and disease.

Abstract

The present article reviews pertinent contributions from the Coronary Physiology Research Group at the Quebec Heart Institute to the understanding of coronary physiology in health and disease. Mechanisms that contribute to regulation of coronary blood flow and its distribution across the ventricular wall are discussed. Data from animal studies of ischemia-reperfusion injury are also presented and discussed in the context of current concepts regarding postischemic myocardial protection strategies. Future research directions regarding the cardiac nervous system and its importance in the regulation of coronary blood flow, cardiac function and myocyte injury during acute myocardial infarction are also discussed.

Entities: Disease

Mesh：

Year: 2007 PMID： 17932582 PMCID： PMC2794464 DOI： 10.1016/s0828-282x(07)71005-x

Source DB: PubMed Journal: Can J Cardiol ISSN： 0828-282X Impact factor: 5.223

Keyword Cloud
References

80 in total

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Authors: V Richard; N Kaeffer; M Hogie; C Tron; T Blanc; C Thuillez
Journal: Br J Pharmacol Date: 1994-11 Impact factor: 8.739

Coronary vasoregulation in health and disease.

1. The early and late phases of ischemic preconditioning: a comparative analysis of their effects on infarct size, myocardial stunning, and arrhythmias in conscious pigs undergoing a 40-minute coronary occlusion.

2. Myocardial protection by brief ischemia in noncardiac tissue.

Review 3. Delayed myocardial protection following ischaemic preconditioning.

Review 4. A "second window of protection" or delayed preconditioning phenomenon: future horizons for myocardial protection?

5. Acute tamponade alters subendo- and subepicardial pressure-flow relations differently during vasodilation.

Review 6. Myocardial preconditioning promises to be a novel approach to the treatment of ischemic heart disease.

7. Preconditioning protects ischemic rabbit heart by protein kinase C activation.

Review 8. Signal transduction in ischemic preconditioning.

Review 9. Does ischemic preconditioning occur in patients?

10. Role of endogenous endothelin in myocardial and coronary endothelial injury after ischaemia and reperfusion in rats: studies with bosentan, a mixed ETA-ETB antagonist.