Literature DB >> 17930473

Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue.

Yuanfang Xie1, Gang Hu, Daisuke Sato, James N Weiss, Alan Garfinkel, Zhilin Qu.   

Abstract

Ventricular fibrillation is a lethal condition caused by multiple chaotically wandering electrical wavelets in the heart, reentering their own and each other's territories. The development of effective therapies requires a detailed understanding of how these reentrant waves are initiated. In this Letter, we demonstrate a novel mechanism for inducing reentry, in which chaos synchronization causes large-scale heterogeneities of refractoriness transverse to the direction of propagation. These regions of increased refractoriness create localized conduction block, which induces spiral wave reentry.

Entities:  

Mesh：

Year:  2007        PMID： 17930473     DOI： 10.1103/PhysRevLett.99.118101

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN： 0031-9007            Impact factor:   9.161


  11 in total

1.  Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos?

Authors:  Daisuke Sato; Lai-Hua Xie; Thao P Nguyen; James N Weiss; Zhilin Qu
Journal:  Biophys J       Date:  2010-08-04       Impact factor: 4.033

Review 2.  Chaos in the genesis and maintenance of cardiac arrhythmias.

Authors:  Zhilin Qu
Journal:  Prog Biophys Mol Biol       Date:  2010-11-13       Impact factor: 3.667

3.  Slow [Na]i Changes and Positive Feedback Between Membrane Potential and [Ca]i Underlie Intermittent Early Afterdepolarizations and Arrhythmias.

Authors:  Yuanfang Xie; Zhandi Liao; Eleonora Grandi; Yohannes Shiferaw; Donald M Bers
Journal:  Circ Arrhythm Electrophysiol       Date:  2015-09-25

4.  Coupled Iterated Map Models of Action Potential Dynamics in a One-dimensional Cable of Cardiac Cells.

Authors:  Shihong Wang; Yuanfang Xie; Zhilin Qu
Journal:  New J Phys       Date:  2008-05-12       Impact factor: 3.729

5.  Nonlinear and Stochastic Dynamics in the Heart.

Authors:  Zhilin Qu; Gang Hu; Alan Garfinkel; James N Weiss
Journal:  Phys Rep       Date:  2014-10-10       Impact factor: 25.600

6.  Mechanisms linking T-wave alternans to spontaneous initiation of ventricular arrhythmias in rabbit models of long QT syndrome.

Authors:  Weiqing Liu; Tae Yun Kim; Xiaodong Huang; Michael B Liu; Gideon Koren; Bum-Rak Choi; Zhilin Qu
Journal:  J Physiol       Date:  2018-03-02       Impact factor: 5.182

Review 7.  Computational approaches to understand cardiac electrophysiology and arrhythmias.

Authors:  Byron N Roberts; Pei-Chi Yang; Steven B Behrens; Jonathan D Moreno; Colleen E Clancy
Journal:  Am J Physiol Heart Circ Physiol       Date:  2012-08-10       Impact factor: 4.733

8.  Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias.

Authors:  Daisuke Sato; Lai-Hua Xie; Ali A Sovari; Diana X Tran; Norishige Morita; Fagen Xie; Hrayr Karagueuzian; Alan Garfinkel; James N Weiss; Zhilin Qu
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-13       Impact factor: 11.205

9.  Bifurcation and chaos in a model of cardiac early afterdepolarizations.

Authors:  Diana X Tran; Daisuke Sato; Arik Yochelis; James N Weiss; Alan Garfinkel; Zhilin Qu
Journal:  Phys Rev Lett       Date:  2009-06-25       Impact factor: 9.161

10.  Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias.

Authors:  Hrayr S Karagueuzian; Thao P Nguyen; Zhilin Qu; James N Weiss
Journal:  Front Physiol       Date:  2013-02-15       Impact factor: 4.566
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.