| Literature DB >> 17929980 |
Kenichi Murai1, Maiko Morishita, Ryo Nakatani, Ozora Kubo, Hiromichi Fujioka, Yasuyuki Kita.
Abstract
The first asymmetric total synthesis of spongotine A is described. The oxidative synthesis of the imidazoline/ketone unit from keto aldehyde and diamine is a key step in this synthesis. The absolute stereochemistry of the asymmetric center of natural spongotine A is revealed as the (S)-configuration.Entities:
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Year: 2007 PMID: 17929980 DOI: 10.1021/jo701668s
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354