Literature DB >> 17928902

Acute B-cell lymphoblastic leukaemia in a 5-month-old boar.

A L Rafferty1, M G Collett, S F Forsyth, E J Neumann, R B Suepaul.   

Abstract

CASE HISTORY: A 5-month-old mixed-breed boar presented with lethargy, weakness and anorexia of 1 week's duration. CLINICAL FINDINGS AND DIAGNOSIS: The boar had an elevated heart rate, slow capillary refill time and cyanotic skin over the ears; it was also severely anaemic. A necropsy revealed scattered petechial haemorrhages, small subcapsular white nodules on the kidneys, a nodule in the parenchyma of one testis, creamy-white bone marrow, a preputial diverticulum, and an ulcer of the pars oesophagea of the stomach. Cytology of peripheral blood and bone marrow identified large numbers of lymphoblasts, which were demonstrated using immunocytochemistry to be of B-cell origin. Histological examination of multiple organs also showed lymphoblastic infiltration. DIAGNOSIS: B-cell lymphoblastic leukaemia with secondary infiltration of lymphoid organs, kidneys, testis and preputial skin. CLINICAL RELEVANCE: This is the fi rst known reported case of acute B-cell lymphoblastic leukaemia in swine.

Entities:  

Mesh:

Year:  2007        PMID: 17928902     DOI: 10.1080/00480169.2007.36776

Source DB:  PubMed          Journal:  N Z Vet J        ISSN: 0048-0169            Impact factor:   1.628


  1 in total

1.  Myelogenous leukemia in adult inbred MHC-defined miniature swine: a model for human myeloid leukemias.

Authors:  Raimon Duran-Struuck; Patricia S Cho; Alexander G S Teague; Brian Fishman; Aaron S Fishman; John S Hanekamp; Shannon G Moran; Krzysztof J Wikiel; Kelly K Ferguson; Diana P Lo; Michael Duggan; J Scott Arn; Bob Billiter; Ben Horner; Stuart Houser; Beow Yong Yeap; Susan V Westmoreland; Thomas R Spitzer; Isabel M McMorrow; David H Sachs; Roderick T Bronson; Christene A Huang
Journal:  Vet Immunol Immunopathol       Date:  2009-12-29       Impact factor: 2.046

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.