Literature DB >> 17928811

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies.

Rosa Bernardi1, Pier Paolo Pandolfi.   

Abstract

The promyelocytic leukaemia (PML) tumour suppressor protein epitomizes the PML-nuclear body (PML-NB) and is crucially required for the proper assembly of this macromolecular nuclear structure. Unlike other, more specialized subnuclear structures such as Cajal and Polycomb group bodies, PML-NBs are functionally promiscuous and have been implicated in the regulation of diverse cellular functions. PML-NBs are dynamic structures that favour the sequestration and release of proteins, mediate their post-translational modifications and promote specific nuclear events in response to various cellular stresses. Recent data suggest that PML-NBs may be heterogeneous in composition, mobility and function.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17928811     DOI： 10.1038/nrm2277

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN： 1471-0072            Impact factor:   94.444


  429 in total

1.  Eradication of acute promyelocytic leukemia-initiating cells by PML/RARA-targeting.

Authors:  Rihab Nasr; Hugues de Thé
Journal:  Int J Hematol       Date:  2010-05-11       Impact factor: 2.490

2.  Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair response.

Authors:  Jayme Salsman; Madhav Jagannathan; Patrick Paladino; Pak-Kei Chan; Graham Dellaire; Brian Raught; Lori Frappier
Journal:  J Virol       Date:  2011-11-09       Impact factor: 5.103

3.  The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.

Authors:  Andrea Rabellino; Brandon Carter; Georgia Konstantinidou; Shwu-Yuan Wu; Alessandro Rimessi; Lauren A Byers; John V Heymach; Luc Girard; Cheng-Ming Chiang; Julie Teruya-Feldstein; Pier Paolo Scaglioni
Journal:  Cancer Res       Date:  2012-03-09       Impact factor: 12.701

4.  Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen and angiogenin interact with common host proteins, including annexin A2, which is essential for survival of latently infected cells.

Authors:  Nitika Paudel; Sathish Sadagopan; Sandhya Balasubramanian; Bala Chandran
Journal:  J Virol       Date:  2011-11-30       Impact factor: 5.103

Review 5.  BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies.

Authors:  Seth M Dever; E Railey White; Matthew C T Hartman; Kristoffer Valerie
Journal:  Cell Cycle       Date:  2012-02-15       Impact factor: 4.534

6.  Functions of the Epstein-Barr virus EBNA1 protein in viral reactivation and lytic infection.

Authors:  Nirojini Sivachandran; Xueqi Wang; Lori Frappier
Journal:  J Virol       Date:  2012-04-04       Impact factor: 5.103

Review 7.  Arc in synaptic plasticity: from gene to behavior.

Authors:  Erica Korb; Steven Finkbeiner
Journal:  Trends Neurosci       Date:  2011-09-30       Impact factor: 13.837

Review 8.  Photobodies in light signaling.

Authors:  Elise K Van Buskirk; Peter V Decker; Meng Chen
Journal:  Plant Physiol       Date:  2011-09-27       Impact factor: 8.340

Review 9.  Genome stability roles of SUMO-targeted ubiquitin ligases.

Authors:  J Heideker; J J P Perry; M N Boddy
Journal:  DNA Repair (Amst)       Date:  2009-02-23

Review 10.  The Arc of cognition: Signaling cascades regulating Arc and implications for cognitive function and disease.

Authors:  Irina Epstein; Steven Finkbeiner
Journal:  Semin Cell Dev Biol       Date:  2018-05       Impact factor: 7.727
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.