| Literature DB >> 17928311 |
Y-C Chang1, C-J Yu, W-J Lee, S-H Kuo, C-H Hsiao, I-S Jan, F-C Hu, H-M Liu, W-K Chan, P-C Yang.
Abstract
The aim of the present study was to investigate whether imprint cytology can improve the diagnostic accuracy of computed tomography-guided transthoracic core biopsy. Between October 1997 and June 2004, thoracic lesions in 622 patients underwent biopsy using 19-gauge coaxial guiding needles and 20-gauge biopsy needles under computed tomography guidance. Touch imprint cytology and histopathology were performed for all biopsy specimens. Of these lesions, 431 (74.1%) were diagnosed as malignant, 151 (25.9%) as benign and 40 (6%) as nondiagnostic. Imprint cytology plus histology shows an improved diagnostic accuracy of 96.4% compared with that of imprint cytology alone (92.3%) or histopathology alone (93.0%). Procedure-related complications requiring further treatment occurred in eight (1.4%) patients. In conclusion, imprint cytology combined with histopathology can improve the diagnostic accuracy of computed tomography-guided transthoracic needle biopsy.Entities:
Mesh：
Year: 2007 PMID： 17928311 DOI： 10.1183/09031936.00038907
Source DB: PubMed Journal: Eur Respir J ISSN： 0903-1936 Impact factor: 16.671