Literature DB >> 17927997

Preparation and properties of mixed micelles made of Pluronic polymer and PEG-PE.

Lingbing Li1, Ye Bang Tan.   

Abstract

Mixed micelles made of Pluronic P105 (P105) and poly(ethylene glycol)-phosphatidyl ethanolamine conjugate (PEG-PE) were prepared. The interaction of Pluronic and PEG-PE was studied and the interaction parameter beta and critical micelle concentration (CMC) were used to evaluate the micellar stability toward dilution. The results showed that certain mixed micelles were more stable than pure Pluronic micelles upon dilution. The mixed micelles were used to trap the poorly soluble anticancer drug camptothecin (CPT). The cytotoxicity of the CPT-loaded mixed micelles against MCF-7 cancer cell was higher than that of CPT-loaded P105 micelles and much higher than that of the free drug.

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Year:  2007        PMID： 17927997     DOI： 10.1016/j.jcis.2007.09.053

Source DB:  PubMed          Journal:  J Colloid Interface Sci        ISSN： 0021-9797            Impact factor:   8.128


  5 in total

1.  Single and mixed poloxamine micelles as nanocarriers for solubilization and sustained release of ethoxzolamide for topical glaucoma therapy.

Authors:  Andreza Ribeiro; Alejandro Sosnik; Diego A Chiappetta; Francisco Veiga; Angel Concheiro; Carmen Alvarez-Lorenzo
Journal:  J R Soc Interface       Date:  2012-04-04       Impact factor: 4.118

2.  Folated synperonic-cholesteryl hemisuccinate polymeric micelles for the targeted delivery of docetaxel in melanoma.

Authors:  Jaleh Varshosaz; Somayeh Taymouri; Farshid Hassanzadeh; Shaghayegh Haghjooy Javanmard; Mahboobeh Rostami
Journal:  Biomed Res Int       Date:  2015-03-08       Impact factor: 3.411

3.  Enhancing the oral bioavailability of biochanin A by encapsulation in mixed micelles containing Pluronic F127 and Plasdone S630.

Authors:  Xiaoyan Wu; Weihong Ge; Tengfei Shao; Weijun Wu; Jian Hou; Li Cui; Jing Wang; Zhenghai Zhang
Journal:  Int J Nanomedicine       Date:  2017-02-22

4.  Docetaxel-Loaded Mixed Micelles and Polymersomes Composed of Poly (caprolactone)-Poly (ethylene glycol) (PEG-PCL) and Poly (lactic acid)-Poly (ethylene glycol) (PEG-PLA): Preparation and In-vitro Characterization.

Authors:  Elham Khodaverdi; Zahra Tayarani-Najaran; Elham Minbashi; Mona Alibolandi; Javad Hosseini; Samaneh Sepahi; Hossein Kamali; Farzin Hadizadeh
Journal:  Iran J Pharm Res       Date:  2019       Impact factor: 1.696

5.  Potential Privilege of Maltodextrin-α-Tocopherol Nano-Micelles in Seizing Tacrolimus Renal Toxicity, Managing Rheumatoid Arthritis and Accelerating Bone Regeneration.

Authors:  Hala M Helal; Wael M Samy; Elbadawy A Kamoun; Esmail M El-Fakharany; Doaa A Abdelmonsif; Rania G Aly; Sana M Mortada; Marwa A Sallam
Journal:  Int J Nanomedicine       Date:  2021-07-14
  5 in total

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