| Literature DB >> 17927190 |
Cristina Nativi1, Martina Cacciarini, Oscar Francesconi, Gloriano Moneti, Stefano Roelens.
Abstract
Acetalic substituents strategically located in a pyrrolic tripodal structure provide a new synthetic receptor endowed with unprecedented affinity for mannosides and the highest selectivity for beta-mannose ever reported for synthetic H-bonding receptors. Binding properties have been determined by NMR, ITC, and ESI-MS techniques, while affinities have been univocally assessed by the BC50(0) parameter, a general descriptor of binding affinity.Entities:
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Year: 2007 PMID： 17927190 DOI： 10.1021/ol701959r
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005