Literature DB >> 17926594

Carcinosarcoma of the parotid gland: report of a case with immunohistochemical findings.

Benjamin D Liess1, Scot Hirschi, Robert P Zitsch, Shellaine Frazier, Angela Konrad.   

Abstract

OBJECTIVES: Carcinosarcoma (true malignant mixed tumor) of the parotid gland is an extremely uncommon tumor composed of both carcinomatous and sarcomatous components. An understanding of this manifestation is crucial to guide management and treatment of this disease.
METHODS: A patient who presented with facial nerve weakness and a painful mass of the parotid gland underwent fine needle aspiration, laboratory testing, and computed tomography of the neck that demonstrated a large parotid malignancy. The patient underwent surgical treatment followed by radiotherapy. Histologic and immunohistochemical examination of the specimen was performed.
RESULTS: This report of a slow-growing parotid mass with otalgia and facial nerve weakness was treated with radical parotidectomy, supraomohyoid neck dissection, and cable graft repair of the excised facial nerve, which was completely encircled by tumor. Postoperative radiotherapy was administered. Histologic and immunohistochemical evaluation demonstrated carcinosarcoma.
CONCLUSIONS: Carcinosarcoma is an unusual tumor of the parotid gland. Treatment generally involves surgery with subsequent radiotherapy. Long-term close follow-up is recommended, for this tumor has a high propensity for both local and regional recurrence and metastasis.

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Year:  2007        PMID: 17926594     DOI: 10.1177/000348940711600913

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  3 in total

1.  Atypical pulmonary metastases from a true malignant mixed tumor of the parotid gland.

Authors:  Wen-Chiung Lin; Chao-Shiang Li; Chih-Kung Lin; Hsian-He Hsu; Tsun-Hou Chang; Tom Yun-Cheng Chen; Guo-Shu Huang
Journal:  Korean J Radiol       Date:  2009-03-03       Impact factor: 3.500

2.  Carcinosarcoma of the parotid gland with mucoepidermoid carcinoma component.

Authors:  Anthony M Santisi; Mark T DiMarcangelo; Xinmin Zhang; Nadir Ahmad; Joshua D Brody
Journal:  Radiol Case Rep       Date:  2020-06-10

3.  Primary Intracranial Manifestation of a Carcinosarcoma.

Authors:  Reza Akhavan-Sigari; Hesam Abdolhoseinpour; Werner Meyer; Veit Rohde; Walter Schulz-Schaeffer
Journal:  Asian J Neurosurg       Date:  2018 Jul-Sep
  3 in total

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