Literature DB >> 17926587

Paranasal sinus osteomas and Gardner's syndrome.

Alan A Z Alexander1, Alpen A Patel, Rick Odland.   

Abstract

OBJECTIVES: Osteomas are common benign tumors of the paranasal sinuses. The origin of these lesions is uncertain. Although most are asymptomatic, symptoms can include headaches, facial pain, rhinorrhea, and sinusitis. Osteomas are also seen as part of Gardner's syndrome, an autosomal dominant disease characterized by intestinal polyposis, osteomas, and cutaneous and soft tissue tumors. In affected individuals, the risk of developing colon cancer approaches 100%. On average, osteomas are detected 17 years before colon polyps appear.
METHODS: Three patients with maxillary or ethmoid osteomas and chronic sinusitis are presented.
RESULTS: One of the patients had evidence of Gardner's syndrome, based on the presence of gastrointestinal symptoms and a positive family history of polyposis.
CONCLUSIONS: Otolaryngologists should be aware of the possibility of Gardner's syndrome in patients with paranasal sinus osteomas. Suspected patients should have a complete workup for Gardner's syndrome, including lower gastrointestinal tract endoscopy, barium enema imaging, and DNA testing.

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Mesh:

Year:  2007        PMID: 17926587     DOI: 10.1177/000348940711600906

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  6 in total

1.  [Pedunculated osteoma of the frontal sinus].

Authors:  P Baumeister; M Niederhagen; E Krause
Journal:  HNO       Date:  2010-03       Impact factor: 1.284

2.  Osteoma of the Middle Turbinate Presenting with Frontal Lobe Abscess and Seizure.

Authors:  Ramandeep Singh Virk; Shikhar Sawhney
Journal:  J Clin Diagn Res       Date:  2017-05-01

3.  Middle turbinate osteoma.

Authors:  Ahmad Daneshi; Maryam Jalessi; Ashkan Heshmatzade-Behzadi
Journal:  Clin Exp Otorhinolaryngol       Date:  2010-12-22       Impact factor: 3.372

4.  Giant osteomas of the ethmoid and frontal sinuses: Clinical characteristics and review of the literature.

Authors:  Ke-Jia Cheng; Shen-Qing Wang; Lin Lin
Journal:  Oncol Lett       Date:  2013-03-08       Impact factor: 2.967

5.  Osteoblastic and hyperostotic craniofacial lesion detected by 99mTc-labeled methylene diphosphonate bone scintigraphy and single-photon emission computed tomography/computed tomography: a pictorial essay.

Authors:  Huijun Ju; Frédéric Paycha
Journal:  Nucl Med Commun       Date:  2021-02-01       Impact factor: 1.698

6.  Orbital cellulitis secondary to giant sino-orbital osteoma: A case report.

Authors:  Abbas Bagheri; Mohadeseh Feizi; Reza Jafari; Mozhgan R Kanavi; Nasim Raad
Journal:  Cancer Rep (Hoboken)       Date:  2020-10-07
  6 in total

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