AIM: To determine stimulated serum anti-Mllerian hormone (AMH) levels in men with different causes of subfertility. SUBJECTS AND METHODS: We prospectively studied 82 subfertile men and 31 controls. The subfertile men underwent a diagnostic procedure to identify the causes of subfertility. Study parameters included testicular volume, levels of follicle-stimulating hormone, luteinizing hormone, total testosterone, prolactin, inhibin B and AMH, and sperm parameters. RESULTS: Clinical diagnoses in subfertile men were idiopathic non-obstructive azoospermia (n = 26, 32%), idiopathic non-obstructive dyspermia (n = 17, 21%), varicocele (n = 16, 20%), cryptorchidism (n = 10, 12%) and other diagnoses (n = 13, 16%). Serum AMH levels in subfertile men were 60% lower than in controls [median (interquartile range) 4.6 (3.6) vs. 11.6 (7.7) ng/ml, p 0.001], with no significant differences among the different groups of subfertile men. CONCLUSIONS: Serum AMH levels differentiate control from subfertile men but not men with different causes of subfertility.
AIM: To determine stimulated serum anti-Mllerian hormone (AMH) levels in men with different causes of subfertility. SUBJECTS AND METHODS: We prospectively studied 82 subfertile men and 31 controls. The subfertile men underwent a diagnostic procedure to identify the causes of subfertility. Study parameters included testicular volume, levels of follicle-stimulating hormone, luteinizing hormone, total testosterone, prolactin, inhibin B and AMH, and sperm parameters. RESULTS: Clinical diagnoses in subfertile men were idiopathic non-obstructive azoospermia (n = 26, 32%), idiopathic non-obstructive dyspermia (n = 17, 21%), varicocele (n = 16, 20%), cryptorchidism (n = 10, 12%) and other diagnoses (n = 13, 16%). Serum AMH levels in subfertile men were 60% lower than in controls [median (interquartile range) 4.6 (3.6) vs. 11.6 (7.7) ng/ml, p 0.001], with no significant differences among the different groups of subfertile men. CONCLUSIONS: Serum AMH levels differentiate control from subfertile men but not men with different causes of subfertility.
Authors: Siri Atma W Greeley; Elizabeth Littlejohn; Aliya N Husain; Darrel Waggoner; Mohan Gundeti; Robert L Rosenfield Journal: Horm Res Paediatr Date: 2017-03-02 Impact factor: 2.852
Authors: Jorunn M Andersen; Hilde Herning; Elin L Aschim; Jøran Hjelmesæth; Tom Mala; Hans Ivar Hanevik; Mona Bungum; Trine B Haugen; Oliwia Witczak Journal: PLoS One Date: 2015-06-12 Impact factor: 3.240
Authors: Dag Eckersten; Christos Tsatsanis; Aleksander Giwercman; Laila Bruun; Mats Pihlsgård; Anders Christensson Journal: Nephron Extra Date: 2017-04-07