M H Becquemin1, J F Bertholon, M Attoui, F Roy, M Roy, B Dautzenberg. 1. Service Central d'Explorations Fonctionnelles Respiratoires, Groupe hospitalier Pitié Salpêtrière, APHP, Université Denis Diderot et UPRES 2397 Paris, France.
Abstract
INTRODUCTION: For several decades a more peripheral distribution of the broncho-pulmonary pathologies related to tobacco has been observed. METHODS: The aim of this study is to examine whether changes in the particle size of cigarette smoke as the result of new manufacturing technologies could play a part in the observed epidemiologic changes through a more distal disposition of smoke particles in the airways. Using a smoking machine and a low pressure electrostatic impactor we measured the particle size of the smoke from six different types of cigarette, representing old and new manufacturing techniques. The effect of a filter was assessed by a size analyser measuring the electrical mobility of the particles. RESULTS: The results show a difference in particle size between the primary smoke inhaled by the smoker, S1 (0.27 +/- 0.03 microm.) and the secondary smoke, S2 inhaled by passive smokers (0.09 +/- 0.01 microm). There is no difference in particle size between the 6 different types of cigarette. Filters dilute the smoke without altering particle size. CONCLUSION: The recent alterations in the distribution of tobacco related pathologies cannot be explained by changes in particle size in cigarette smoke. The explanation has to sought elsewhere.
INTRODUCTION: For several decades a more peripheral distribution of the broncho-pulmonary pathologies related to tobacco has been observed. METHODS: The aim of this study is to examine whether changes in the particle size of cigarette smoke as the result of new manufacturing technologies could play a part in the observed epidemiologic changes through a more distal disposition of smoke particles in the airways. Using a smoking machine and a low pressure electrostatic impactor we measured the particle size of the smoke from six different types of cigarette, representing old and new manufacturing techniques. The effect of a filter was assessed by a size analyser measuring the electrical mobility of the particles. RESULTS: The results show a difference in particle size between the primary smoke inhaled by the smoker, S1 (0.27 +/- 0.03 microm.) and the secondary smoke, S2 inhaled by passive smokers (0.09 +/- 0.01 microm). There is no difference in particle size between the 6 different types of cigarette. Filters dilute the smoke without altering particle size. CONCLUSION: The recent alterations in the distribution of tobacco related pathologies cannot be explained by changes in particle size in cigarette smoke. The explanation has to sought elsewhere.
Authors: Chelsea R Navarrette; Joseph H Sisson; Elizabeth Nance; Diane Allen-Gipson; Justin Hanes; Todd A Wyatt Journal: J Aerosol Med Pulm Drug Deliv Date: 2012-01-26 Impact factor: 2.849
Authors: Isabella Anna Joubert; Mark Geppert; Litty Johnson; Robert Mills-Goodlet; Sara Michelini; Evgeniia Korotchenko; Albert Duschl; Richard Weiss; Jutta Horejs-Höck; Martin Himly Journal: Front Immunol Date: 2020-06-30 Impact factor: 7.561