Literature DB >> 17925635

Severe multiple extensive postburn contractures: a simultaneous approach with total scar tissue excision and resurfacing with dermal regeneration template.

Andrea Figus1, Jorge Leon-Villapalos, Bruce Philp, Peter Dziewulski.   

Abstract

Deep partial or full-thickness burns if untreated, neglected, or managed conservatively can develop dysfunctional scar contractures with severe deformities and significant reduction in patient's activities of daily life. These burn sequelae can require multistage procedures to restore anatomy and function. These include single scar release, use of skin grafts, skin expansion, regional or free musculocutaneous or fasciocutaneous flaps to achieve adequate functional improvement. The use of dermal regeneration template (Integra), initially used in primary burns reconstruction, has been already described and compared in single scar contracture-releasing procedures, but to our knowledge, it has not been used in the simultaneous releasing of multiple severe extensive postburn contractures. A simultaneous approach with total scar tissue excision and resurfacing with Integra may reduce the number of operations and the prolonged time period of treatment required by conventional procedures of multistage scar contracture release. A 7-year-old girl, who developed severe postburn scar contractures involving the right upper limb, right axilla, neck, and face after healing of a deep 16% total body surface area burn injury, was treated with this approach. Restoration of anatomy and function, with significant improvement in the range of movement of the involved regions, was achieved in a relatively short period of time (15 weeks) with limited donor-site morbidity and preservation of donor areas for possible future procedures. Total scar tissue excision and resurfacing with Integra should be considered as a valid option in case of simultaneous management of severe multiple extensive scar contractures.

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Year:  2007        PMID: 17925635     DOI: 10.1097/BCR.0b013e318159eb8c

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  6 in total

1.  Dermal regenerative matrix use in burn patients: A systematic review.

Authors:  Katie E Hicks; Minh Nq Huynh; Marc Jeschke; Claudia Malic
Journal:  J Plast Reconstr Aesthet Surg       Date:  2019-08-08       Impact factor: 2.740

Review 2.  Cell secretomes for wound healing and tissue regeneration: Next generation acellular based tissue engineered products.

Authors:  Nur Izzah Md Fadilah; Muhammad Syahiran Mohd Abdul Kader Jailani; Muhd Aliff Iqmal Badrul Hisham; Nithiaraj Sunthar Raj; Sharen Aini Shamsuddin; Min Hwei Ng; Mh Busra Fauzi; Manira Maarof
Journal:  J Tissue Eng       Date:  2022-07-28       Impact factor: 7.940

3.  [Cervical burns sequelae: epidemiological, clinical and therapeutic aspects in Morocco].

Authors:  Amine Rafik; Hakim Chabak; Mounia Diouri; Naïma Bahechar; Abdessamad Chlihi
Journal:  Pan Afr Med J       Date:  2015-04-27

4.  Epidermal stem cells cultured on collagen-modified chitin membrane induce in situ tissue regeneration of full-thickness skin defects in mice.

Authors:  Yan Shen; Libing Dai; Xiaojian Li; Rong Liang; Guangxiong Guan; Zhi Zhang; Wenjuan Cao; Zhihe Liu; Shirley Mei; Weiguo Liang; Shennan Qin; Jiake Xu; Honghui Chen
Journal:  PLoS One       Date:  2014-02-07       Impact factor: 3.240

Review 5.  Tissue engineering in burn scar reconstruction.

Authors:  Ppm van Zuijlen; Klm Gardien; Meh Jaspers; E J Bos; D C Baas; Ajm van Trier; E Middelkoop
Journal:  Burns Trauma       Date:  2015-09-30

6.  Cell-free fat extract promotes tissue regeneration in a tissue expansion model.

Authors:  Mingwu Deng; Xiangsheng Wang; Ziyou Yu; Yizuo Cai; Wei Liu; Guangdong Zhou; Xiansong Wang; Zheyuan Yu; Wei Li; Wen Jie Zhang
Journal:  Stem Cell Res Ther       Date:  2020-02-04       Impact factor: 6.832

  6 in total

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